Surgical Approaches for Cervical Myelopathy
Surgical decompression is strongly recommended for moderate to severe cervical myelopathy (mJOA score ≤12), with benefits maintained for at least 5 years and up to 15 years postoperatively. 1
Classification and Treatment Decision Algorithm
- Cervical myelopathy is classified as mild (mJOA score >12), moderate, or severe (mJOA score ≤12) based on the degree of impairment in arm and leg function 2
- Mild cervical myelopathy can be treated with either surgical decompression or nonoperative therapy for the first 3 years after diagnosis 2, 1
- Moderate to severe cervical myelopathy should be treated with surgical decompression to prevent further neurological deterioration 1
- Delaying surgical intervention in patients with moderate to severe myelopathy can lead to irreversible spinal cord damage 1
Anterior Surgical Approaches
Anterior Cervical Discectomy and Fusion (ACDF)
Anterior Corpectomy and Fusion
- Recommended for 3-segment disease 1, 3
- Provides improved decompression for patients with retrovertebral disease 3
- Ideal for patients with kyphosis or significant neck pain 3
- Subtotal corpectomy with reconstruction can improve neurological scores from an average of 7.9 preoperatively to 13.4 at 15-year follow-up 1
- Risk of pseudarthrosis in approximately 10.9% of cases 1, 4
- Inadequate stabilization can lead to cage movement and hardware failure 4
Posterior Surgical Approaches
Laminoplasty
- Preserves motion and reduces axial neck pain 1, 3
- Appropriate for multilevel compression (≥3 levels) 3
- Requires lordotic cervical alignment to be effective 5
- Risk of post-surgical kyphosis in approximately 10% of patients 1, 6
- Risk of C5 nerve palsy, especially when laminae are elevated to an angle >60° 1, 6
Laminectomy with Fusion
Approach Selection Factors
- Number of involved levels (1-2 levels: anterior approach; ≥3 levels: posterior approach) 1, 3
- Location of compression (anterior vs. posterior) 5
- Cervical alignment (kyphosis favors anterior approach; lordosis favors posterior approach) 5
- Developmental narrowing of the canal (favors posterior approach if lordotic) 5
- Presence of instability (requires fusion) 5
Complications and Considerations
- Inadequate surgical decompression has been reported in 10% of cases, with a higher rate (23%) associated with anterior approaches 7
- Posterior or combined approaches showed no cases of inadequate decompression in one study 7
- Post-surgical kyphosis occurs in approximately 10% of patients after laminoplasty 1, 6
- Pseudarthrosis can occur in approximately 10.9% of cases after corpectomy 1, 4
- C5 nerve palsy can develop after surgery, especially with posterior approaches 1, 6
Revision Surgery Options
- Anterior revision with plate stabilization can be effective for pseudarthrosis, with 83.3% good/excellent outcomes 4
- Posterior approach revision can be a viable option for hardware failure, with a 94% fusion rate compared to 45% with anterior revision 4
- Combined anterior-posterior approaches may be necessary for complex cases with kyphosis and developmental narrowing 5
Outcomes
- Surgical intervention is superior to conservative management for moderate to severe CSM 8
- Benefits of surgery for moderate to severe cervical myelopathy are maintained for at least 5 years and up to 15 years postoperatively 2, 1
- Patients with severe myelopathy show significant improvement after surgical intervention 1
- Early recognition and treatment before the onset of significant spinal cord damage is essential for optimal outcomes 8