Is creatine (creatine monohydrate) effective for osteoporosis prevention?

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Last updated: March 25, 2025View editorial policy

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From the Research

Creatine supplementation is not a recommended first-line treatment for osteoporosis prevention, and its effectiveness is not supported by the most recent and highest quality evidence. The most recent study, 1, published in 2022, discusses the importance of osteoporosis prevention and treatment but does not mention creatine as a recommended treatment.

Key Points to Consider

  • Osteoporosis is a significant public health problem, and prevention is crucial to reducing the risk of fractures and related morbidity and mortality.
  • Established approaches to osteoporosis prevention include adequate calcium and vitamin D intake, weight-bearing exercise, and prescription medications when indicated.
  • While creatine supplementation may have some benefits for muscle strength and bone health, it is not a substitute for established treatments and should not be relied upon as the primary means of osteoporosis prevention.
  • The evidence for creatine supplementation in osteoporosis prevention is limited, and more research is needed to fully understand its potential benefits and risks.

Recommendations for Osteoporosis Prevention

  • Ensure adequate calcium and vitamin D intake, either through diet or supplementation, as recommended by studies such as 1 and 2.
  • Engage in regular weight-bearing exercise, such as resistance training, to improve bone strength and reduce the risk of falls.
  • Consider prescription medications, such as bisphosphonates, when indicated, to reduce the risk of fractures.
  • Consult with a healthcare provider before starting any new supplements, including creatine, especially if you have kidney problems or other health concerns.

References

Research

The clinician's guide to prevention and treatment of osteoporosis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2022

Research

Osteoporosis prevention, diagnosis, and therapy.

NIH consensus statement, 2000

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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