What are the initial steps in managing a critically ill patient?

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Last updated: October 21, 2025View editorial policy

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Initial Management of Critically Ill Patients

The initial management of critically ill patients must follow the systematic ABCDE approach (Airway, Breathing, Circulation, Disability, Exposure), with airway assessment and stabilization being the absolute first priority, as failure to secure an adequate airway will make all other interventions futile. 1, 2

Airway Management

  • Assess airway patency immediately and intervene if there are signs of obstruction, altered consciousness, hypoventilation, or hypoxemia 3
  • Position the patient optimally (head-up position unless contraindicated) to maximize airway patency 4
  • Clear the airway of secretions or foreign bodies using suction equipment 4
  • Consider early intubation if there are signs of respiratory insufficiency including dyspnea, desaturation, or stridor 5
  • Use waveform capnography for all intubations as failure to use capnography contributes to >70% of ICU airway-related deaths 4, 3
  • Modified rapid sequence induction (RSI) is the most appropriate technique for intubating critically ill patients 4
  • The most experienced available operator should manage the airway to minimize complications 5

Breathing Assessment and Support

  • Administer high-flow oxygen immediately to prevent hypoxemia 4
  • Consider continuous positive airway pressure (CPAP) for preoxygenation as it reduces myocardial depression and left ventricular afterload 4
  • Monitor oxygen saturation continuously with pulse oximetry 4
  • Assess respiratory rate, pattern, and effort 2
  • Listen for breath sounds bilaterally to detect pneumothorax or other abnormalities 6
  • For mechanically ventilated patients, confirm endotracheal tube position and secure it properly 4
  • Set appropriate ventilator parameters (FiO2, PEEP, respiratory frequency, tidal volume) and ensure alarms are active 4

Circulation Assessment and Support

  • Establish reliable intravenous or intraosseous access immediately 4
  • Monitor blood pressure, heart rate, and ECG continuously 4
  • Assess for signs of shock (hypotension, tachycardia, poor peripheral perfusion) 2
  • Administer a rapid infusion of 500ml crystalloid solution if no signs of cardiac failure are present 4
  • Have vasopressors immediately available for patients with suspected hemodynamic instability 3
  • Assign a team member specifically to monitor and manage hemodynamic status 4

Disability (Neurological) Assessment

  • Assess level of consciousness using the AVPU scale (Alert, Voice, Pain, Unresponsive) or Glasgow Coma Scale 2
  • Check pupillary size and reactivity 2
  • Record neurological status prior to airway management, especially in patients with head injury 4
  • Consider sedation and/or neuromuscular blocking agents if the patient is agitated or combative 4

Exposure and Environmental Control

  • Perform a complete examination to identify other injuries or sources of deterioration 2
  • Maintain normothermia 2
  • Insert a nasogastric tube in patients with ileus, intestinal obstruction, or those requiring mechanical ventilation 4
  • Insert a urinary catheter for patients requiring strict fluid management or receiving diuretics 4

Team-Based Approach

  • Implement a checklist-based approach to ensure all critical steps are completed 4
  • Assign clear roles to team members (airway management, circulation management, medication administration) 4
  • Document the time when interventions begin, as significant time may pass unnoticed during airway crises 4
  • Communicate clearly within the team about the patient's status and planned interventions 4
  • Anticipate potential deterioration and prepare equipment and medications accordingly 4

Special Considerations

  • For burn patients with airway compromise, early intubation is necessary before extensive facial swelling develops 3
  • In patients with cervical spine injury, maintain manual in-line stabilization during intubation 3
  • For trauma victims, maintain spinal immobilization unless the absence of significant spinal injury has been reliably verified 4
  • In traumatic chest injury with suspected tension pneumothorax, perform needle decompression prior to intubation if there are signs of hemodynamic compromise 3

Common Pitfalls to Avoid

  • Delaying airway intervention when signs of respiratory compromise are present 3
  • Failing to use waveform capnography to confirm correct endotracheal tube placement 4
  • Inadequate preoxygenation before intubation attempts 4
  • Multiple intubation attempts leading to trauma and airway deterioration 4
  • Insufficient monitoring of hemodynamic status during and after interventions 4
  • Inadequate team communication and role assignment 4

References

Research

[Emergency Resuscitation Techniques:Airway, Breathing, and Circulation].

No shinkei geka. Neurological surgery, 2023

Guideline

Intubation Without Blood Pressure Measurement for Airway Protection

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Intubation Guidelines for Krait Bite

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Respiratory assessment in critically ill patients: airway and breathing.

British journal of nursing (Mark Allen Publishing), 2009

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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