Treatment for Costochondritis
NSAIDs are the first-line treatment for costochondritis, to be used at maximum tolerated and approved dosage with evaluation of treatment response after 2-4 weeks. 1
Pharmacological Management
First-Line Treatment
- Start with NSAIDs at the lowest effective dose for the shortest possible period to minimize risks 1
- Consider topical NSAIDs to minimize systemic side effects, particularly useful for localized pain 1
- Regular dosing of acetaminophen (paracetamol) may be used as an alternative or adjunct when NSAIDs are insufficient, contraindicated, or poorly tolerated 1
Second-Line Treatment
- If inadequate response after 2-4 weeks, consider switching to a different NSAID or adding acetaminophen 1
- For persistent focal areas of tenderness, consider local corticosteroid injections directed to the site of inflammation 1
- Short courses of oral prednisolone may be considered as a bridging option while awaiting the effect of other agents 1
Important Cautions
- Monitor for gastrointestinal, liver, and cardiorenal toxicity with prolonged NSAID use, particularly in elderly patients and those with comorbidities 1
- Avoid long-term use of systemic glucocorticoids due to potential adverse effects 1
- For patients with increased gastrointestinal risk, use non-selective NSAIDs plus a gastroprotective agent, or a selective COX-2 inhibitor 1
Non-Pharmacological Interventions
Physical Modalities
- Apply local heat or cold applications to the affected area for symptomatic relief 1
- Regular exercise and physical therapy should be considered as part of a comprehensive treatment plan 1
- Stretching exercises have shown promising results in reducing pain in costochondritis patients 2
- Manual therapy and soft tissue mobilization techniques may be beneficial, especially in cases that don't respond to conventional treatment 3, 4
Patient Education
- Provide education about the condition and reassurance about its typically benign and self-limiting nature 1, 5
- Advise patients to avoid activities that produce chest muscle overuse 5
Special Considerations
Atypical or Persistent Cases
- For costochondritis that doesn't resolve within the expected timeframe (typically several weeks), consider referral to physical therapy for impairment-based examination and treatment 4
- Physical therapy approaches including manual therapy to the cervicothoracic spine and ribcage, combined with therapeutic exercise, may facilitate resolution of persistent costochondritis 4
Differential Diagnosis
- Rule out more serious causes of chest pain, particularly in patients older than 35 years or those with risk factors for coronary artery disease 5
- Be aware that coronary artery disease can be present in 3-6% of adult patients with chest wall tenderness 5
- Infectious costochondritis is rare but should be considered in cases with purulent discharge, systemic symptoms, or failure to respond to standard treatment 6
Remember that while costochondritis is usually self-limited and benign, proper diagnosis and appropriate treatment can significantly reduce pain and improve quality of life for affected patients.