What is the treatment for costochondritis?

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Last updated: October 21, 2025View editorial policy

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Treatment for Costochondritis

NSAIDs are the first-line treatment for costochondritis, to be used at maximum tolerated and approved dosage with evaluation of treatment response after 2-4 weeks. 1

Pharmacological Management

First-Line Treatment

  • Start with NSAIDs at the lowest effective dose for the shortest possible period to minimize risks 1
  • Consider topical NSAIDs to minimize systemic side effects, particularly useful for localized pain 1
  • Regular dosing of acetaminophen (paracetamol) may be used as an alternative or adjunct when NSAIDs are insufficient, contraindicated, or poorly tolerated 1

Second-Line Treatment

  • If inadequate response after 2-4 weeks, consider switching to a different NSAID or adding acetaminophen 1
  • For persistent focal areas of tenderness, consider local corticosteroid injections directed to the site of inflammation 1
  • Short courses of oral prednisolone may be considered as a bridging option while awaiting the effect of other agents 1

Important Cautions

  • Monitor for gastrointestinal, liver, and cardiorenal toxicity with prolonged NSAID use, particularly in elderly patients and those with comorbidities 1
  • Avoid long-term use of systemic glucocorticoids due to potential adverse effects 1
  • For patients with increased gastrointestinal risk, use non-selective NSAIDs plus a gastroprotective agent, or a selective COX-2 inhibitor 1

Non-Pharmacological Interventions

Physical Modalities

  • Apply local heat or cold applications to the affected area for symptomatic relief 1
  • Regular exercise and physical therapy should be considered as part of a comprehensive treatment plan 1
  • Stretching exercises have shown promising results in reducing pain in costochondritis patients 2
  • Manual therapy and soft tissue mobilization techniques may be beneficial, especially in cases that don't respond to conventional treatment 3, 4

Patient Education

  • Provide education about the condition and reassurance about its typically benign and self-limiting nature 1, 5
  • Advise patients to avoid activities that produce chest muscle overuse 5

Special Considerations

Atypical or Persistent Cases

  • For costochondritis that doesn't resolve within the expected timeframe (typically several weeks), consider referral to physical therapy for impairment-based examination and treatment 4
  • Physical therapy approaches including manual therapy to the cervicothoracic spine and ribcage, combined with therapeutic exercise, may facilitate resolution of persistent costochondritis 4

Differential Diagnosis

  • Rule out more serious causes of chest pain, particularly in patients older than 35 years or those with risk factors for coronary artery disease 5
  • Be aware that coronary artery disease can be present in 3-6% of adult patients with chest wall tenderness 5
  • Infectious costochondritis is rare but should be considered in cases with purulent discharge, systemic symptoms, or failure to respond to standard treatment 6

Remember that while costochondritis is usually self-limited and benign, proper diagnosis and appropriate treatment can significantly reduce pain and improve quality of life for affected patients.

References

Guideline

Costochondritis Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Stretching exercises for costochondritis pain.

Giornale italiano di medicina del lavoro ed ergonomia, 2009

Research

IMPAIRMENT BASED EXAMINATION AND TREATMENT OF COSTOCHONDRITIS: A CASE SERIES.

International journal of sports physical therapy, 2017

Research

Costochondritis: diagnosis and treatment.

American family physician, 2009

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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