What is the treatment for paronychia?

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Treatment of Paronychia

The treatment of paronychia should be tailored based on whether it is acute or chronic, with first-line therapy consisting of warm soaks with dilute vinegar (50:50 dilution) or 2% povidone-iodine applied twice daily for 10-15 minutes. 1, 2

Classification and Initial Assessment

  • Evaluate severity based on redness, edema, discharge, and granulation tissue 1
  • Check for presence of pus or abscess formation which would require drainage 1
  • Assess for predisposing factors such as ingrown toenail (onychocryptosis) 1
  • Determine if acute (less than 6 weeks) or chronic (6 weeks or longer) as treatment approaches differ 3

Treatment Algorithm for Acute Paronychia

Conservative Management (First-Line)

  • Implement antiseptic soaks with dilute vinegar (50:50 dilution) or povidone-iodine for 10-15 minutes twice daily 1, 2
  • Apply topical 2% povidone-iodine twice daily to the affected area 2
  • Use mid to high potency topical steroid ointment to nail folds twice daily to reduce inflammation 2
  • For edema and pain, apply warm soaks with or without Burow solution or 1% acetic acid 3

When Abscess is Present

  • Drainage is mandatory when abscess is present 3
  • Options for drainage range from using a hypodermic needle to a wide incision with a scalpel 3
  • After drainage, continue warm soaks and topical antibiotics 1

Antimicrobial Therapy

  • Oral antibiotics are usually not needed if adequate drainage is achieved unless the patient is immunocompromised or has a severe infection 3
  • For moderate to severe infection, select antibiotics based on likely pathogens 1
  • Be aware that secondary bacterial or mycological superinfections are present in up to 25% of cases 2, 1

For Ingrown Toenail with Paronychia

  • Use techniques such as dental floss nail technique to separate the lateral nail edge from underlying tissue 2
  • Consider splinting with a flexible tube or acrylic treatment with gutter splint for onychocryptosis 2

Treatment Algorithm for Chronic Paronychia

First-Line Therapy

  • Apply high-potency topical corticosteroids alone or combined with topical antibiotics 2
  • Regular application of emollients to cuticles and periungual tissues 2
  • Identify and eliminate exposure to irritants (acids, alkalis, and other chemicals) 3, 4

For Refractory Cases

  • For recurrent, severe, or treatment-refractory cases, consider intralesional triamcinolone acetonide 2
  • Topical timolol 0.5% gel twice daily under occlusion has shown benefit in some cases 2
  • Consider topical calcineurin inhibitors as an alternative to steroids 3

Surgical Options for Chronic Paronychia

  • Surgical treatment may be necessary for recalcitrant cases 4
  • Options include en bloc excision of the proximal nail fold or eponychial marsupialization 4
  • The Swiss roll technique may be effective for severe chronic paronychia 5

Management of Complications

Pyogenic Granuloma

  • For granulation tissue formation, use silver nitrate chemical cauterization 2
  • Consider scoop shave removal with hyfrecation for excessive granulation tissue 2
  • Cryotherapy could also be considered in the treatment of pyogenic granuloma 2

Prevention of Recurrence

  • Gentle nail care, including trimming nails straight across and not too short 2
  • Avoid repeated friction, trauma, and excessive pressure 2
  • Wear comfortable well-fitting shoes and cotton socks 2
  • Use protective gloves during activities involving water or chemicals 1
  • Patient education is paramount to reduce recurrence 3

Follow-up Recommendations

  • Reassess after 2 weeks of treatment 1
  • If no improvement is seen, consider referral to dermatology or podiatry 1
  • For chronic paronychia, be aware that treatment may take weeks to months 3
  • Investigate for unusual causes such as malignancy in cases unresponsive to standard treatment 6

References

Guideline

Management of Paronychia of the Toenail

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Acute and Chronic Paronychia.

American family physician, 2017

Research

Management of chronic paronychia.

Indian journal of dermatology, 2014

Research

Swiss roll technique for treatment of paronychia.

Techniques in hand & upper extremity surgery, 2011

Research

Toenail paronychia.

Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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