Selecting the Appropriate Ultrasound Examination
For comprehensive evaluation of suspected deep venous thrombosis (DVT), a complete duplex ultrasound protocol from thigh to ankle with Doppler at selected sites is recommended as the standard examination.1
Deep Venous Thrombosis (DVT) Ultrasound
Standard Protocol Recommendations
- Complete duplex ultrasound (CDUS) from thigh to ankle with Doppler evaluation at selected sites is the recommended standard examination for suspected DVT 1
- This comprehensive protocol is superior to limited examinations as it evaluates both proximal and calf veins, providing better diagnostic information 1
- Limited protocols that do not include calf veins are not recommended as they require a second study in 5-7 days to safely exclude DVT 1
When Point-of-Care Ultrasound is Necessary
- If complete duplex ultrasound is not available, a point-of-care ultrasound consisting of extended compression ultrasound (ECUS) from thigh to knee is appropriate 1
- After a negative ECUS, a complete duplex ultrasound in 5-7 days is required to safely exclude DVT 1
- If ultrasound is completely unavailable, anticoagulation before a confirmatory ultrasound is a safe strategy 1
Follow-Up Recommendations
- For patients with calf DVT who are managed expectantly, a repeat scan at 1 week (or sooner if symptoms worsen) is recommended 1
- For negative complete duplex ultrasound with persistent symptoms, a repeat scan in 5 days to 1 week is advised 1
- For technically compromised studies, a repeat scan in 5-7 days is recommended if more than minor limitations exist 1
Emergency Ultrasound Applications
Core Applications in Emergency Settings
- Emergency ultrasound has established core applications including trauma, intrauterine pregnancy, abdominal aortic aneurysm, cardiac, biliary, urinary tract, DVT, soft-tissue/musculoskeletal, thoracic, ocular, and procedural guidance 1
- These applications can be classified as resuscitative, diagnostic, symptom-based, procedure guidance, or therapeutic/monitoring 1
Point-of-Care Protocols
- Point-of-care ultrasound protocols should be standardized to minimize underdiagnosis of critical conditions 1
- For DVT evaluation, a single standardized point-of-care examination enhances patient safety and clinician confidence 1
Early Pregnancy Evaluation
- For stable patients in the first trimester with abdominal pain or vaginal bleeding, ultrasound is indicated 2
- Even with β-hCG levels below the discriminatory threshold (typically 1,500 mIU/mL), ultrasound may still be beneficial with approximately 33% sensitivity and 98% specificity for diagnosing intrauterine pregnancy 1, 2
- The decision to perform ultrasound should consider the patient's ability to arrange appropriate follow-up 2
Critical Care Ultrasound Applications
Pleural Effusion
- Ultrasound should be used to complement physical examination and chest radiography to diagnose and localize pleural effusions 1
- Ultrasound guidance should be used to assist in drainage of effusions, particularly small or loculated ones 1
Lung Pathology
- A systematic approach incorporating bedside ultrasound may be a primary diagnostic modality for ICU patients with respiratory failure 1
- Ultrasound has high sensitivity and specificity (>90%) for diagnosing alveolar consolidation 1
Pneumothorax Detection
- Ultrasound has sensitivity and specificity exceeding 85% for diagnosing pneumothorax, compared to 30-75% for conventional radiography 1
- Visualization of comet tail artifacts reliably excludes pneumothorax, while demonstration of a lung point without lung sliding confirms the diagnosis 1
Surveillance Ultrasound in Specific Populations
Cancer Surveillance
- For patients who have undergone partial or radical nephrectomy for kidney cancer, abdominal ultrasound is recommended within 3-12 months after surgery 1
- For patients with stage II kidney cancer, ultrasound may be used for surveillance every 3-6 months for at least 3 years 1
Genetic Syndrome Surveillance
- In patients with DICER1 syndrome, biannual to annual abdominal ultrasound is recommended starting at birth to screen for cystic nephroma or renal tumors 1
- Annual or semiannual pelvic ultrasound throughout childhood and adulthood should be considered in these patients to screen for ovarian sex cord-stromal tumors 1
- Thyroid ultrasound starting at age 8 years should be considered in DICER1 syndrome patients 1
Practical Considerations
- Ultrasound is widely available, extremely safe, portable, and inexpensive compared to other imaging modalities 3
- Modern ultrasound has progressed beyond anatomical imaging to include tissue perfusion studies, molecular imaging, and therapeutic applications 3
- For vascular access procedures, providers should use real-time, two-dimensional ultrasound guidance with a high-frequency linear transducer 4
Common Pitfalls to Avoid
- Avoid using static ultrasound alone to mark needle insertion sites for vascular access procedures 4
- Avoid limited DVT protocols that exclude calf veins, as they require follow-up studies and may miss isolated femoral vein DVTs 1
- Be cautious with terminology - use "chronic postthrombotic change" to describe residual material that persists after acute DVT to avoid potential overtreatment of prior thrombus 1