Differential Diagnosis for Breast Lump without Redness or Tender

Single Most Likely Diagnosis

• Fibroadenoma: This is a common benign breast tumor, especially in young women. It presents as a firm, mobile, and painless lump, which matches the description given.

Other Likely Diagnoses

• Cyst: Breast cysts are fluid-filled sacs within the breast and are very common. They can present as a lump and are usually painless, though they can become tender during the menstrual cycle.
• Lipoma: A benign tumor made up of fat tissue, which can occur in the breast and present as a soft, movable lump.
• Fibrocystic Changes: These are benign changes in the breast tissue that can cause lumps, which are often multiple and bilateral. They can be associated with hormonal changes and are very common.

Do Not Miss Diagnoses

• Breast Cancer: Although less likely to present without any other symptoms, breast cancer can occasionally manifest as a single, painless lump. It is crucial to consider this diagnosis to ensure timely investigation and treatment if necessary.
• Phyllodes Tumor: A rare tumor of the breast that can be benign, borderline, or malignant. It presents as a rapidly growing lump and is important not to miss due to its potential for malignancy.

Rare Diagnoses

• Hamartoma: A benign breast tumor made up of a mixture of glandular, fibrous, and fatty tissues. It is rare and presents as a lump.
• Pseudoangiomatous Stromal Hyperplasia (PASH): A rare benign condition of the breast that can cause a lump. It is more common in young women and can mimic other breast lesions.
• Adenoma: A rare benign tumor of the breast glandular tissue, which can present as a lump.