What is the management approach for an infected ingrown toenail?

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Management of Infected Ingrown Toenail

For infected ingrown toenails, treatment should include warm antiseptic soaks, topical povidone-iodine, appropriate oral antibiotics, and consideration of partial nail avulsion for severe cases. 1, 2

Initial Assessment and Classification

  • Evaluate severity based on parameters including redness, edema, discharge, and granulation tissue 1
  • Check for presence of pus or abscess formation which would require drainage 1
  • Assess for secondary bacterial or mycological superinfections, which are present in up to 25% of cases 3

Conservative Management (Mild Cases)

  • Implement warm antiseptic soaks with dilute vinegar (50:50 dilution) or povidone-iodine for 10-15 minutes twice daily 1, 2
  • Apply topical 2% povidone-iodine twice daily to the affected area 1, 2
  • Use mid to high-potency topical steroid ointment to nail folds twice daily to reduce inflammation 1, 2
  • Consider gutter splinting with a plastic tube placed on the lateral edge of the nail to provide immediate pain relief 2, 4
  • Place cotton wisps or dental floss under the ingrown nail edge to separate it from the underlying tissue 2, 5

Antimicrobial Therapy (For Infection)

  • For infected ingrown toenails, oral antibiotics should be selected based on likely pathogens 1, 2
  • Start with cephalexin as first-line therapy for coverage against Staphylococcus aureus and other gram-positive organisms 1, 2
  • If initial treatment fails, consider switching to sulfamethoxazole-trimethoprim (Bactrim) for broader coverage including MRSA 1
  • Obtain bacterial cultures if pus is present to guide antibiotic selection 2
  • Apply topical antibiotics such as bacitracin 1-3 times daily to the affected area 6

Management of Granulation Tissue

  • For pyogenic granuloma formation, consider scoop shave removal with hyfrecation 1, 2
  • Silver nitrate application is effective for chemical cauterization of excessive granulation tissue 1, 2, 7
  • For recurrent, severe, or treatment-refractory cases, consider intralesional triamcinolone acetonide 1
  • Topical timolol 0.5% gel twice daily under occlusion has shown benefit in some cases 1

Surgical Intervention (For Moderate to Severe Cases)

  • Partial nail avulsion is indicated for persistent pain, drainage beyond 2-4 weeks, or failure of conservative management 2, 5
  • Partial nail avulsion combined with phenolization (chemical matricectomy) is more effective at preventing recurrence than surgical excision alone 5, 4
  • Alternative surgical options include electrocautery, radiofrequency, and carbon dioxide laser ablation of the nail matrix 5, 8
  • Note that oral antibiotics before or after phenolization do not improve outcomes 5

Prevention of Recurrence

  • Proper nail trimming technique: cut nails straight across, not too short 1, 2
  • Avoid repeated friction, trauma, and excessive pressure 1, 2
  • Wear comfortable well-fitting shoes and cotton socks 1, 2
  • Use protective gloves during activities involving water or chemicals 1, 2
  • Regular application of emollients to cuticles and periungual tissues 1, 2
  • Maintain good foot hygiene to prevent recurrent infections 5, 4

Follow-up

  • Reassess after 2 weeks of treatment 1, 2
  • If no improvement is seen, consider referral to dermatology or podiatry for further evaluation 1, 2
  • Monitor for signs of infection including increased pain, redness, swelling, or purulent drainage 2

References

Guideline

Management of Ingrown Toenail

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Medical Management of Ingrown Nails

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Ingrown Toenail Management.

American family physician, 2019

Research

Management of the ingrown toenail.

American family physician, 2009

Research

How I Manage Ingrown Toenails.

The Physician and sportsmedicine, 1983

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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