Treatment of Large Bowel Obstruction
Large bowel obstruction is primarily treated by surgeons, with specific management approaches determined by the underlying cause, patient condition, and presence of complications. 1
Initial Management
- All patients with large bowel obstruction require supportive care including IV fluid resuscitation, nasogastric tube decompression, and Foley catheter placement for monitoring urine output 1
- Multidetector CT with intravenous contrast is essential for determining the cause, location, and complications of the obstruction 1
- Close monitoring for signs of ischemia or perforation through clinical assessment, laboratory values, and imaging findings is crucial 1
Cause-Specific Treatment Approaches
Sigmoid Volvulus
- For sigmoid volvulus without ischemia or perforation, endoscopic detorsion followed by same-admission sigmoid colectomy with primary anastomosis is recommended 2
- Endoscopic detorsion alone should be reserved only for high-surgical-risk patients, though recurrence rates reach up to 71% 2
- Immediate surgical intervention is necessary for ischemic volvulus or failed derotation 2
- Laparoscopic approach has limitations due to the absence of fixation and excessive length of the sigmoid colon 2
Cecal Volvulus
Diverticular Disease
- Resection with primary anastomosis is preferred after successful conservative management, regardless of bowel preparation status 2
- Conservative therapy or Hartmann procedure may be more appropriate for high-risk patients 2
Malignant Obstruction
- Colorectal cancer accounts for over 60% of all large bowel obstructions 4
- For left-sided colonic cancer, self-expanding metallic stents can serve as a bridge to elective surgery, offering better short-term outcomes with lower stoma rates 2
- Resection with primary anastomosis is recommended for patients without significant risk factors or perforation 2
- For high-risk patients or those with perforation, a staged procedure such as Hartmann procedure is preferred 2
- For extraperitoneal rectal cancer, postponing primary tumor resection and creating a diverting stoma allows for proper staging and appropriate neoadjuvant treatment 2
- Anastomotic leak rates range from 2.2-12%, comparable to the 2-8% rate after elective procedures 2
Special Considerations
Surgical Approach
- Laparoscopic surgery should be limited to selected cases in specialized centers for malignant large bowel obstruction 2
- For frail patients with sigmoid volvulus, a limited left lower quadrant transverse laparotomy incision without laparoscopy may be beneficial to avoid risks associated with pneumoperitoneum 5
Colonic Pseudo-obstruction
- Distinguishing true mechanical obstruction from pseudo-obstruction (functional obstruction without mechanical blockage) is critical as management differs significantly 6, 7
- Water-soluble contrast studies are important in making this distinction 7
- Pseudo-obstruction can usually be managed non-operatively with treatment of underlying conditions 7
Monitoring and Follow-up
- Regular reassessment is essential to determine if surgical intervention becomes necessary for patients managed conservatively 1
- Immediate surgery is necessary if signs of clinical deterioration develop, such as peritonism, increasing white blood cell count, or rising lactate 1
Pitfalls to Avoid
- Delaying surgical intervention when signs of ischemia or perforation are present can significantly increase mortality 3
- Failing to recognize the difference between mechanical obstruction and pseudo-obstruction can lead to unnecessary surgery 6
- Underestimating the high recurrence risk (up to 71%) when managing sigmoid volvulus with endoscopic detorsion alone 2