Differential Diagnosis for Non-Necrotic Mesenteric Lymphadenopathy with Fat Stranding
- Single Most Likely Diagnosis
- Mesenteric Panniculitis (Sclerosing Mesenteritis): This condition is characterized by inflammation of the mesenteric fat, which can lead to lymphadenopathy and fat stranding on imaging. It often presents with abdominal pain and can be associated with other conditions such as autoimmune disorders or previous abdominal surgery.
- Other Likely Diagnoses
- Infectious Ileitis (e.g., Yersinia, Salmonella): Certain infections can cause mesenteric lymphadenopathy and inflammation of the surrounding fat. These infections are often accompanied by symptoms of gastroenteritis.
- Inflammatory Bowel Disease (IBD): Conditions like Crohn's disease can cause lymphadenopathy and fat stranding due to chronic inflammation of the bowel wall and surrounding tissues.
- Diverticulitis: Inflammation of a diverticulum in the colon can lead to localized lymphadenopathy and fat stranding, especially if the diverticulum is located in the sigmoid colon.
- Do Not Miss Diagnoses
- Lymphoma: Although less common, lymphoma can present with mesenteric lymphadenopathy and should be considered to avoid delayed diagnosis and treatment.
- Tuberculosis: Abdominal tuberculosis can cause lymphadenopathy and may involve the mesenteric nodes, making it a critical diagnosis not to miss, especially in endemic areas or in immunocompromised patients.
- Rare Diagnoses
- Whipple's Disease: A rare, systemic bacterial infection that can cause malabsorption and may involve the mesenteric lymph nodes.
- Castleman Disease: A rare disorder that can cause lymphadenopathy, including in the mesenteric region, and can be associated with systemic symptoms.
- Kaposi's Sarcoma: In immunocompromised patients, Kaposi's sarcoma can involve the lymph nodes and gastrointestinal tract, leading to lymphadenopathy and other abdominal symptoms.