What tests are recommended at a 1-week newborn check-up?

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Last updated: October 23, 2025View editorial policy

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Recommended Tests for 1-Week Newborn Check-up

At the 1-week newborn check-up, essential tests include a complete physical examination with growth parameter assessment, jaundice evaluation, and review of newborn screening results. 1

Physical Examination Components

  • Complete head-to-toe examination with careful attention to growth parameters (weight, length, head circumference) plotted on appropriate growth charts 2
  • Assessment of umbilical cord healing, especially if a ligature or rubber cord ring was used instead of a clamp to prevent trauma 1
  • Evaluation of skin for jaundice, which should be quantified with transcutaneous bilirubin (TcB) or total serum bilirubin (TSB) measurement if present 1
  • Neurological assessment including tone, posture, primitive reflexes, and spontaneous movements 2, 3
  • Cardiovascular examination with attention to heart murmurs, which are common in the immediate newborn period and often represent transition from fetal to neonatal circulation 3

Laboratory Tests

  • Review of newborn screening test results if already available 2, 4
  • For jaundiced infants:
    • Measure total and direct bilirubin levels 1
    • Consider additional testing based on bilirubin levels, including blood type, Coombs' test, complete blood count, and smear if the infant is receiving phototherapy or if bilirubin is rising rapidly 1
  • No routine blood tests are recommended for healthy infants without concerning symptoms 5, 6

Special Considerations

  • For infants with jaundice beyond 3 weeks or sick infants, measure total and direct/conjugated bilirubin to identify cholestasis 1
  • Check results of newborn thyroid and galactosemia screening in infants with prolonged jaundice 1
  • For premature infants, growth assessments should be corrected for gestational age 1
  • If there are any birth trauma wounds, ensure they are properly covered with cling film or a non-adherent dressing to prevent further trauma 1

Common Pitfalls to Avoid

  • Visual estimation of jaundice without objective measurement can lead to errors, particularly in darkly pigmented infants 1
  • Failing to interpret bilirubin levels according to the infant's age in hours 1
  • Overlooking subtle findings that may indicate serious conditions; the vast majority of infants are healthy, but findings predictive of future health problems can be subtle 7
  • Unnecessary repeated examinations - research shows that a second thorough examination in the early neonatal period identifies important findings in only 0.5% of cases, though hip examination remains important 5

Follow-up Recommendations

  • Schedule the next well-child visit at 1 month of age 2
  • Provide anticipatory guidance on basic infant care including feeding, skin care, and temperature measurement 2
  • Ensure caregivers understand developmental expectations for the next period 2

Remember that the 1-week check-up is primarily focused on assessing the infant's transition to extrauterine life, evaluating growth, and identifying any early concerns that require intervention.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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