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Differential Diagnosis for Constant Runny Nose

Single Most Likely Diagnosis

  • Allergic Rhinitis: This is the most common cause of a constant runny nose, often triggered by allergens such as pollen, dust mites, or pet dander, leading to chronic inflammation and nasal discharge.

Other Likely Diagnoses

  • Viral Upper Respiratory Tract Infection (URTI): Common colds can cause a runny nose due to viral infection of the nasal mucosa, leading to increased mucus production.
  • Non-Allergic Rhinitis: Includes various forms of rhinitis not caused by allergies, such as vasomotor rhinitis, where the nasal blood vessels are overly sensitive, or hormonal rhinitis, related to hormonal changes.
  • Sinusitis: Inflammation or infection of the sinuses can lead to a constant runny nose, as the sinuses drain into the nasal cavity.

Do Not Miss Diagnoses

  • Nasal Tumor or Cancer: Although rare, a tumor in the nasal cavity can cause persistent nasal discharge. Early detection is crucial for effective treatment.
  • CSF Leak: A cerebrospinal fluid leak can present with a constant, clear nasal discharge, which is a serious condition requiring prompt medical attention.
  • Granulomatosis with Polyangiitis (GPA): A form of vasculitis that can affect the nasal passages and sinuses, leading to chronic nasal discharge and destruction of nasal tissue.

Rare Diagnoses

  • Primary Ciliary Dyskinesia: A genetic disorder affecting the cilia in the respiratory tract, leading to chronic respiratory infections and nasal discharge.
  • Sjögren's Syndrome: An autoimmune disorder that can cause dryness in the eyes and mouth but sometimes presents with nasal symptoms due to inflammation of the nasal mucosa.
  • Fungal Sinusitis: A fungal infection of the sinuses, more common in immunocompromised individuals, which can cause chronic nasal discharge and other sinus symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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