Testicular Cancer Referral After Ultrasound Diagnosis
Patients with testicular cancer diagnosed via ultrasound should be promptly referred to a urologist for definitive management. 1, 2
Initial Diagnostic Process
- A solid mass in the testis identified by physical exam or imaging should be managed as a malignant neoplasm until proven otherwise 1
- Scrotal ultrasound with Doppler is the recommended initial imaging study for patients with a suspicious testicular mass 1, 2
- Any hypoechoic mass with vascular flow on ultrasound is highly suggestive of malignancy 1
- Before referral, serum tumor markers (alpha-fetoprotein [AFP], human chorionic gonadotropin [hCG], lactate dehydrogenase [LDH]) should be drawn 1, 3
Specialist Referral
- Urologist referral is the first step in management for definitive diagnosis and surgical treatment (radical inguinal orchiectomy) 2, 4
- Radical inguinal orchiectomy with division of the spermatic cord at the internal inguinal ring is both diagnostic and therapeutic 2, 5
- A scrotal approach should be avoided as it is associated with higher local recurrence rates 2
Pre-Treatment Considerations
- Patients should be counseled about risks of hypogonadism and infertility before any treatment 1, 2
- Sperm banking should be offered before any therapeutic intervention, including surgery 1, 2
- In patients without a normal contralateral testis or with known subfertility, sperm banking should be considered prior to orchiectomy 1
Multidisciplinary Management
- After initial urologic management, patients may require referral to:
- The National Comprehensive Cancer Network recommends management by a multidisciplinary team at high-volume, experienced medical centers 4
Post-Orchiectomy Pathway
- Following orchiectomy and pathological diagnosis, further management is guided by:
- Treatment options may include active surveillance, chemotherapy, retroperitoneal lymph node dissection, or radiation therapy 4, 5
Common Pitfalls to Avoid
- Delaying referral to a urologist when a solid testicular mass is identified on ultrasound 1, 6
- Failing to obtain tumor markers before orchiectomy, which can make it difficult to establish baseline values 3
- Not discussing sperm banking before treatment, which may lead to irreversible infertility 2, 5
- Using a scrotal approach for orchiectomy rather than the recommended inguinal approach 2