Management of Ventricular Fibrillation with Pulse
Ventricular fibrillation with a pulse should be immediately treated with synchronized cardioversion, starting at 100J for monomorphic VT, with stepwise energy increases if the initial shock is unsuccessful. 1
Initial Assessment and Management
- Ventricular fibrillation with a pulse is a rare but life-threatening arrhythmia that requires immediate intervention to prevent progression to pulseless VF and cardiac arrest 2
- Quickly assess hemodynamic stability while preparing for cardioversion; if the patient becomes unstable during assessment, proceed immediately to electrical therapy 1
- Establish IV access as soon as possible without delaying electrical therapy 2
- Apply cardiac monitoring to confirm the diagnosis and differentiate from other wide-complex tachycardias 1
Electrical Therapy
- For monomorphic VT (regular form and rate) with a pulse, synchronized cardioversion is the treatment of choice, starting at 100J for monophasic or biphasic waveforms 1
- If the first shock is unsuccessful, increase the energy in a stepwise fashion (e.g., 200J, then 300J, then 360J) 1
- For polymorphic VT (irregular VT) with a pulse, treat as VF using unsynchronized high-energy shocks (defibrillation doses) 1
- Do not use synchronized cardioversion for VF as the device may not sense a QRS wave and thus a shock may not be delivered 1
Pharmacological Therapy
- If cardioversion is delayed or unsuccessful, consider antiarrhythmic medications:
- Intravenous amiodarone: Initial dose of 150mg over 10 minutes, followed by maintenance infusion of 1mg/min for 6 hours, then 0.5mg/min 3
- Alternative option: Intravenous procainamide for stable monomorphic VT (loading dose of 20-50 mg/min until arrhythmia suppressed, hypotension occurs, QRS widens by >50%, or maximum dose of 17mg/kg is given) 1
- For VT thought to be related to myocardial ischemia, intravenous lidocaine may be reasonable 1
Special Considerations
- In patients with Wolff-Parkinson-White syndrome and pre-excitation, avoid administering beta-blockers, calcium channel blockers, or digoxin as these may accelerate the ventricular response and precipitate VF 1, 4
- For VT in the setting of acute myocardial infarction, consider immediate revascularization as this can reduce the frequency and complexity of arrhythmias 1
- If VF with pulse progresses to pulseless VF, immediately switch to ACLS protocol for cardiac arrest with high-quality CPR and unsynchronized shocks 2
Post-Conversion Care
- After successful cardioversion, monitor the patient closely for recurrence, which is common (up to 74% of patients may experience refibrillation) 5
- Correct any underlying electrolyte abnormalities, particularly potassium and magnesium 4
- Consider maintenance antiarrhythmic therapy to prevent recurrence 1
- Evaluate for and treat underlying causes such as acute coronary syndrome, cardiomyopathy, or electrolyte disturbances 4
Common Pitfalls to Avoid
- Do not delay cardioversion in hemodynamically unstable patients 1
- Never use synchronized cardioversion for VF or polymorphic VT as synchronization may not occur, delaying effective treatment 1
- Avoid using calcium channel blockers in patients with impaired ventricular function or heart failure as these may worsen hemodynamic status 1
- Do not administer multiple antiarrhythmic medications simultaneously without expert consultation, as this increases the risk of proarrhythmia and hemodynamic compromise 1