Recommended Fluid Bolus Calculation for Pediatric Patients
For pediatric patients requiring fluid resuscitation, administer isotonic crystalloid (0.9% NaCl) boluses of 20 mL/kg, which can be repeated up to 60 mL/kg in the first hour based on clinical response. 1
Initial Fluid Selection and Administration
- Use isotonic crystalloid solutions (e.g., normal saline or lactated Ringer's) as the first-choice fluid for initial resuscitation in pediatric patients 1
- Calculate the initial fluid bolus based on the child's weight at 20 mL/kg 1
- Administer fluid boluses rapidly using either:
Fluid Administration Technique
- For shock states, deliver each 20 mL/kg bolus over 5-10 minutes 1, 3
- For children with septic shock, consider administering each 20 mL/kg bolus over 15-20 minutes to potentially reduce the risk of requiring mechanical ventilation 3
- For children weighing >40 kg, be aware that achieving the recommended rapid infusion rates may be more challenging 2
Monitoring Response and Additional Boluses
- Reassess the patient after each fluid bolus to evaluate response and prevent fluid overload 4
- Look for positive response indicators including:
- ≥10% increase in systolic/mean arterial blood pressure
- ≥10% reduction in heart rate
- Improvement in mental status, peripheral perfusion, and urine output 4
- Continue fluid administration with additional 20 mL/kg boluses as long as there is hemodynamic improvement without signs of fluid overload 1, 4
- Watch for signs of fluid overload including development of increased work of breathing, rales, gallop rhythm, or hepatomegaly 1
Special Considerations for Different Clinical Scenarios
- For hypovolemic shock: Administer up to 60 mL/kg in the first hour if needed, with repeated 20 mL/kg boluses 1
- For septic shock: Consider administering up to 40-60 mL/kg in the first hour, titrated to response 1, 3
- For gastroenteritis with dehydration: Consider using 5% dextrose in normal saline for the 20 mL/kg bolus to help reduce ketosis, though this may not affect hospitalization rates 5
- For trauma patients: Use 20 mL/kg boluses of isotonic crystalloid and involve a qualified surgeon early 1
Intravenous Access Considerations
- If peripheral IV access cannot be established quickly, use intraosseous (IO) access for fluid administration 1
- Central venous access may be used but be aware that resistance in longer catheters may make rapid bolus administration more difficult 1
Pitfalls to Avoid
- Avoid using hypotonic solutions for initial resuscitation as they can worsen hyponatremia 1
- Don't use etomidate for sedation during intubation in patients with septic shock as it's associated with higher mortality rates 1
- Don't rely on gravity-based fluid administration during acute resuscitation as it delivers fluid too slowly 2
- Avoid delaying fluid resuscitation while waiting for central access; use peripheral or IO access immediately 1