Treatment of Paronychia
The treatment of paronychia should follow a graded approach based on severity, with warm soaks, topical antiseptics, antibiotics, and surgical drainage for more severe cases.
Classification and Assessment
- Paronychia is an inflammation of the folds of tissue surrounding the nail of a toe or finger, and may be classified as either acute or chronic 1
- Evaluate severity based on parameters including redness, edema, discharge, and granulation tissue 2
- Check for presence of pus or abscess formation which would require drainage 2
- Assess for predisposing factors such as ingrown toenail (onychocryptosis) 2
Treatment Algorithm by Severity
Grade 1 (Mild) Paronychia
- Implement warm water soaks for 15 minutes 3-4 times daily or white vinegar soaks (1:1 white vinegar:water) for 15 minutes daily 3, 2
- Apply topical 2% povidone-iodine twice daily to the affected area 3
- Use mid to high potency topical steroid ointment to nail folds twice daily to reduce inflammation 2
- Reassess after 2 weeks; if reactions worsen or do not improve, proceed to next step 3
Grade 2 (Moderate) Paronychia
- Continue treatment with topical agents as above 3
- Obtain bacterial/viral/fungal cultures if infection is suspected 3
- Apply topical very potent steroids, antifungals, antibiotics and/or antiseptics (preferably as combination preparations) 3
- Start oral antibiotics if signs of infection are present 3
- Reassess after 2 weeks; if reactions worsen or do not improve, proceed to next step 3
Grade 3 (Severe) Paronychia
- Interrupt any causative medications until condition improves to Grade 0/1 3
- Obtain bacterial/viral/fungal cultures if infection is suspected 3
- Continue topical treatments as above 3
- Consider partial nail avulsion for severe cases 3
- Swab any pus for culture and prescribe appropriate antibiotics 3
- Consider surgical intervention for drainage 3
Special Considerations
Acute Paronychia
- Main factor associated with development is direct or indirect trauma to the cuticle or nail fold 1
- Treatment options include warm compresses, topical antibiotics with or without corticosteroids, oral antibiotics, or surgical incision and drainage for more severe cases 1
- Secondary bacterial or mycological superinfections are present in up to 25% of cases 3
Chronic Paronychia
- Represents a multifactorial inflammatory reaction of the proximal nail fold to irritants and allergens 1
- Apply high-potency topical corticosteroids which have been found more effective than antifungals in chronic cases 2, 4
- Consider intralesional triamcinolone acetonide for recalcitrant cases 2
- Topical timolol 0.5% gel twice daily under occlusion has shown benefit in some cases 3
- For recalcitrant chronic paronychia, en bloc excision of the proximal nail fold or eponychial marsupialization may be options 1
Prevention of Recurrence
- Keep hands and feet as dry as possible; avoid prolonged soaking in water 2, 4
- Avoid nail trauma/injury and cutting nails too short 3, 2
- Moisturize hands and feet regularly with emollients applied to cuticles and periungual tissues 3
- Wear protective gloves during wet work or exposure to irritants 3
- Wear comfortable well-fitting shoes that protect nails without being restrictive 3
- Regular trimming of the nails ensuring that they are straight and not too short 3
Common Pitfalls to Avoid
- Don't overlook potential secondary bacterial or mycological superinfections, which are present in up to 25% of cases 3
- Don't delay surgical drainage when abscess is present, as this can lead to worsening infection 4
- Don't forget to address underlying causes in chronic paronychia, such as occupational exposures or systemic conditions 4, 5
- Don't rely solely on oral antibiotics without adequate drainage when an abscess is present 4
- Don't neglect patient education on preventive measures, which is paramount to reduce recurrence 4