Recommended Dosing for Nasonex (Mometasone Furoate)
The recommended dose of Nasonex (mometasone furoate) is age-dependent: 1 spray per nostril daily for children 2-11 years and 2 sprays per nostril daily for individuals 12 years and older. 1
Age-Specific Dosing Guidelines
- For adults and children 12 years and older: 2 sprays per nostril once daily (total daily dose: 200 μg) 1
- For children 2-11 years old: 1 spray per nostril once daily (total daily dose: 100 μg) 1
- For adults 18 years and older with nasal polyps: 2 sprays per nostril twice daily (total daily dose: 400 μg) 1
Administration Technique
- Shake the spray bottle well before each use 2
- Prime the bottle before first use or if not used for one week 2
- Blow nose gently to clear nostrils before administration 2
- Close one nostril and insert spray tip into the other nostril, aiming slightly away from the center of the nose 2
- While sniffing gently, press down on spray nozzle once or twice according to dosing instructions 2
- Repeat in the other nostril 2
Clinical Efficacy
- Mometasone furoate nasal spray is effective for both seasonal and perennial allergic rhinitis 1
- The 200 μg once daily dose has been identified as the optimal dose for adults in clinical trials, with no additional benefit seen at higher doses 3
- For children 6-11 years, studies have shown that 100 μg once daily is the most appropriate therapeutic dosage, with 200 μg providing no additional benefit 4
Safety Profile and Side Effects
- Common side effects include headache, viral infection, pharyngitis, epistaxis (nosebleeds), and cough 1
- Contraindicated in patients with history of hypersensitivity to the medication or its components 1
- Studies have shown no evidence of hypothalamic-pituitary-adrenal axis suppression at recommended doses 4
- Mometasone furoate has negligible systemic activity at therapeutic doses 5
Special Considerations
- For optimal results, use regularly rather than as-needed to maintain symptom control 6
- Onset of action may be delayed (approximately 12 hours) with maximal efficacy reached in days to weeks 6
- If symptoms do not improve after one week of use, discontinue and consult a healthcare provider 2
- For children who need to use Nasonex for longer than two months per year, consultation with a physician is recommended 2