How to negotiate the splenic flexure during colonoscopy?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Negotiating the Splenic Flexure During Colonoscopy

The most effective technique for negotiating the splenic flexure during colonoscopy is to use a combination of variable stiffness colonoscope settings, patient positioning changes, and targeted abdominal pressure application. 1

Understanding the Challenge

The splenic flexure represents a common technical challenge during colonoscopy due to:

  • Its acute angulation and fixed anatomical position 1
  • Attachment to the spleen via the splenocolic ligament, creating tension during manipulation 2
  • Risk of loop formation, which can cause patient discomfort and impede advancement 3

Recommended Techniques

1. Variable Stiffness Colonoscope Usage

  • Activate maximum stiffness once the sigmoid colon has been negotiated and the colonoscope has been straightened with the tip in the proximal descending colon 1
  • This reduces the number of ancillary maneuvers and shortens insertion time through the proximal colon 1
  • The stiffening mechanism is most effective when used at the splenic flexure (71% of cases) 1

2. Patient Positioning

  • Change patient position from left lateral to supine when approaching the splenic flexure 3
  • This position change is successful in advancing the endoscope tip in approximately 68% of difficult cases 3
  • Consider right lateral positioning in particularly challenging cases to provide better exposure of the left upper quadrant 4

3. Abdominal Pressure Application

  • Apply external abdominal pressure to prevent loop formation 3
  • Use a stepwise approach:
    • Begin with non-specific pressure to the region where looping is developing (more successful in left colon - 78% success rate) 3
    • Progress to endoscopically observed specific pressure near the tip if needed 3
  • Most pressure applications need to last less than 30 seconds 3

4. Insufflation Management

  • Use CO₂ insufflation rather than air to minimize bowel distension and patient discomfort 5
  • Insufflate judiciously to avoid barotrauma 5

Risk Minimization

  • Recognize when to abort the procedure if unusual difficulty is encountered in traversing the splenic flexure 5
  • Be aware that splenic injury is a rare but serious complication (0.020-0.034% of procedures) with 30-day mortality of 3.6% 2
  • Gentle progression and avoidance of excessive force can prevent complications 5

Technical Considerations

  • Ensure adequate bowel preparation (at least 90% of patients should have excellent or adequate preparation) 5, 6
  • Maintain minimum withdrawal time of 6 minutes (10 minutes aspirational) for thorough examination 5
  • Follow appropriate sedation guidelines based on patient age 5

When to Seek Assistance

  • If multiple attempts to negotiate the splenic flexure are unsuccessful despite using the techniques above 5
  • When patient experiences significant pain despite appropriate sedation 5
  • When loop formation persists despite abdominal pressure and position changes 3

By systematically applying these techniques, most colonoscopists can successfully navigate the splenic flexure while minimizing patient discomfort and risk of complications.

References

Research

The technique of abdominal pressure in total colonoscopy.

Gastrointestinal endoscopy, 1991

Research

Right lateral position for laparoscopic splenic flexure mobilization.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2011

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Bowel Preparation Quality for Colonoscopy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.