Can the COVID-19 (Coronavirus Disease 2019) vaccine and the meningococcal (Neisseria meningitidis) vaccine be administered together or how long should we wait to give the meningococcal vaccine after the COVID-19 vaccine?

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Last updated: October 28, 2025View editorial policy

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COVID-19 and Meningococcal Vaccines Can Be Administered Together Without Waiting Period

COVID-19 vaccines and meningococcal vaccines can be administered simultaneously or at any interval without waiting between doses. 1

Timing of Administration

  • Inactivated vaccines like meningococcal vaccines (MenACWY) can be administered either simultaneously or at any time before or after COVID-19 vaccines without requiring a waiting period 1
  • Simultaneous administration of all indicated vaccines increases the likelihood of complete vaccination and provides timely protection against preventable diseases 1
  • The immune response to inactivated vaccines is not affected by other vaccines, allowing for concurrent administration 1

COVID-19 Vaccination Recommendations

  • For persons aged ≥6 months, the Advisory Committee on Immunization Practices (ACIP) recommends vaccination with 2024-2025 COVID-19 vaccines as authorized or approved 2
  • Depending on previous vaccination history and immune status, different dosing schedules apply:
    • Previously unvaccinated immunocompetent persons aged ≥5 years need 1 dose of Moderna or Pfizer-BioNTech, or 2 doses of Novavax (for those ≥12 years) 2
    • Those who previously received ≥1 COVID-19 vaccine dose need 1 additional dose of any 2024-2025 COVID-19 vaccine, administered ≥8 weeks after the last dose 2

Meningococcal Vaccination Recommendations

  • Meningococcal vaccines are recommended based on age and risk factors 2
  • For healthy adolescents, MenACWY is recommended at age 11-12 years with a booster dose at age 16 years 2
  • For persons at increased risk (e.g., with complement deficiencies, asplenia, HIV), specific schedules apply:
    • For persons aged ≥10 years, MenACWY is recommended as a 2-dose primary series administered 8 weeks apart 2
    • MenB vaccines may also be indicated depending on risk factors 2

Practical Implementation

  • Document all vaccines administered in the patient's permanent medical record 1
  • Different manufacturers' serogroup B-containing vaccines are not interchangeable; subsequent doses of MenB should be from the same manufacturer 3
  • Do not mix individual vaccines in the same syringe unless specifically approved for mixing by the FDA 1

Special Considerations

  • For persons with certain medical conditions (e.g., asplenia, complement deficiencies), additional doses and specific timing may be required for both COVID-19 and meningococcal vaccines 2
  • For immunocompromised patients, more doses of COVID-19 vaccine may be recommended (e.g., 3-dose primary series for unvaccinated persons aged 6 months-11 years) 2
  • Meningococcal disease cases dropped during the COVID-19 pandemic but have rebounded in some regions after restrictions were lifted, highlighting the importance of maintaining vaccination coverage 4, 5

Conclusion

When administering both COVID-19 and meningococcal vaccines, healthcare providers can give them simultaneously or at any interval without concerns about interference between the vaccines 1. This approach maximizes vaccination opportunities and ensures timely protection against both diseases.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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