Dry Eye Syndrome: This condition is characterized by insufficient lubrication on the surface of the eye, leading to discomfort, blurred vision, and difficulty focusing, especially in the afternoon after prolonged periods of screen time or other activities that reduce tear production.

Myopia (Nearsightedness): Although myopia typically presents with difficulty seeing distant objects clearly, it can also cause eye strain and blurred vision, especially after prolonged near work, which might worsen in the afternoon.
Hyperopia (Farsightedness): Similar to myopia, hyperopia can cause blurred vision and difficulty focusing, particularly on close objects, and symptoms might become more noticeable in the afternoon due to prolonged use of the eyes.
Presbyopia: An age-related condition that affects the eye's ability to focus on close objects, often becoming noticeable in the early to mid-40s. Symptoms can worsen in the afternoon due to eye fatigue.
Astigmatism: This refractive error can cause blurred vision at all distances and might become more bothersome in the afternoon due to prolonged visual tasks.

Diabetic Retinopathy: A complication of diabetes that can lead to blurred vision among other symptoms. It's crucial to diagnose and manage to prevent vision loss.
Glaucoma: A group of eye conditions that damage the optic nerve, often due to abnormally high pressure in the eye. Glaucoma can cause blurred vision and is a medical emergency if acute angle-closure glaucoma is suspected.
Migraine: Some types of migraines can cause visual disturbances, including blurred vision and difficulty focusing, which might be accompanied by headache and other neurological symptoms.
Multiple Sclerosis: This autoimmune disease can affect the optic nerve and cause a variety of visual symptoms, including blurred vision, double vision, and loss of vision.

Thyroid Ophthalmopathy: Associated with Graves' disease, this condition can cause bulging of the eyes, blurred vision, and double vision due to inflammation of tissues around the eye.
Papilledema: Swelling of the optic disc caused by increased intracranial pressure, which can lead to transient blurred vision and other visual disturbances.
Uveitis: Inflammation of the uvea, the middle layer of the eye, which can cause blurred vision, eye pain, and sensitivity to light.
Optic Neuritis: Inflammation of the optic nerve that can cause pain and temporary vision loss in one eye, which might be perceived as blurred vision or difficulty focusing.