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Differential Diagnosis for Hair Loss in a 35-year-old Female

Single Most Likely Diagnosis

  • Androgenetic Alopecia (Female Pattern Hair Loss): This is the most common cause of hair loss in women, characterized by thinning of hair over the mid-frontal scalp. It is often associated with hormonal changes and genetic predisposition.

Other Likely Diagnoses

  • Telogen Effluvium: A condition that causes excessive hair shedding due to stress, hormonal changes, or medical conditions. It is reversible and often resolves on its own.
  • Alopecia Areata: An autoimmune condition that leads to patchy hair loss. It can be triggered by stress, hormonal changes, or other autoimmune diseases.
  • Thyroid Disorders: Both hypothyroidism and hyperthyroidism can cause hair loss due to the impact of thyroid hormones on hair growth.
  • Polycystic Ovary Syndrome (PCOS): A hormonal disorder that can cause hair loss, acne, and irregular menstrual cycles.

Do Not Miss Diagnoses

  • Lupus: A chronic autoimmune disease that can cause hair loss, skin rashes, and other systemic symptoms. Early diagnosis and treatment are crucial to prevent long-term damage.
  • Thyroid Cancer: Although rare, thyroid cancer can cause hair loss, weight loss, and other systemic symptoms. Prompt diagnosis and treatment are essential.
  • Pituitary Tumors: Tumors in the pituitary gland can disrupt hormone production, leading to hair loss, menstrual irregularities, and other symptoms.

Rare Diagnoses

  • Trichotillomania: A psychological disorder characterized by compulsive hair pulling, leading to hair loss.
  • Traction Alopecia: Hair loss caused by constant pulling or tension on the hair, often due to hairstyles like braids or ponytails.
  • Loose Anagen Syndrome: A rare condition that causes hair to fall out easily due to a defect in the hair growth cycle.
  • Hair loss due to Nutritional Deficiencies: Deficiencies in vitamins like biotin, vitamin D, or minerals like iron can cause hair loss.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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