Allergic Reaction: This is often the most common cause of facial puffiness, resulting from an allergic response to substances like food, pollen, or insect bites, leading to increased fluid retention and swelling.

Fluid Retention: Conditions such as premenstrual syndrome (PMS), pregnancy, or the use of certain medications can lead to fluid retention, causing puffiness in the face.
Sinusitis: Inflammation of the sinuses can cause facial puffiness, especially around the eyes and cheeks, due to the accumulation of mucus and swelling of the sinus tissues.
Dental Infections: Abscesses or infections in the teeth or gums can spread to cause facial swelling and puffiness.
Hormonal Changes: Hormonal fluctuations during menopause, thyroid disorders, or other endocrine conditions can lead to changes in fluid balance and facial puffiness.

Angioedema: A severe, potentially life-threatening allergic reaction that can cause rapid swelling of the face, lips, tongue, and throat, which requires immediate medical attention.
Cellulitis: A bacterial skin infection that can cause redness, swelling, and warmth of the skin, which can be serious if not treated promptly.
Orbital Cellulitis: An infection of the tissues surrounding the eye, which can lead to severe complications, including vision loss, if not treated aggressively.

Myxedema: A condition associated with hypothyroidism, characterized by thickening of the skin and underlying tissues, leading to a puffy appearance, particularly on the face.
Sarcoidosis: A rare autoimmune disease that can cause inflammation and swelling in various parts of the body, including the face.
Wegener's Granulomatosis (Granulomatosis with Polyangiitis): A rare autoimmune disorder that can cause inflammation of the blood vessels, leading to facial puffiness among other symptoms.