Iron Supplements Containing 20mg of Elemental Iron
Ferrous fumarate tablets containing 20mg of elemental iron are available as a low-dose iron supplement option for iron deficiency anemia treatment.
Available Iron Supplements with 20mg Elemental Iron
- Low-dose iron supplements containing approximately 20mg of elemental iron include:
Benefits of Low-Dose Iron Supplementation
- Low-dose iron supplementation (20-30mg elemental iron) can be effective while causing fewer gastrointestinal side effects compared to traditional higher doses 2, 3
- Recent evidence suggests that lower doses may be as effective as higher doses due to hepcidin regulation of iron absorption 1, 3
- For pregnant women, low-dose iron supplementation (20mg) has been shown to have minimal gastrointestinal side effects while still being effective for prophylaxis 2
Dosing Considerations
- Once-daily dosing is preferred over multiple daily doses, as oral doses of 60mg elemental iron stimulate hepcidin levels, reducing subsequent iron absorption by 35-45% 1, 4
- For patients experiencing gastrointestinal side effects with traditional iron preparations, alternate-day dosing may improve absorption and tolerability 4, 3
- Morning administration is preferred over afternoon or evening dosing due to circadian variations in hepcidin levels 3
Comparing Iron Formulations
- Traditional ferrous salts (ferrous sulfate, ferrous fumarate, ferrous gluconate) differ in elemental iron content:
- Newer formulations like ferric maltol and ferrous bisglycinate may offer better tolerability at lower doses 1, 2
Monitoring Recommendations
- Regular monitoring of hemoglobin is recommended approximately every 4 weeks until normalization 4
- After hemoglobin normalization, oral iron should be continued for 2-3 months to replenish iron stores 1, 4
- A hemoglobin rise of at least 10 g/L after 2 weeks of daily oral iron therapy predicts successful treatment response 4
Common Pitfalls and Caveats
- Tea and coffee inhibit iron absorption and should not be consumed within an hour of taking iron supplements 1
- Higher doses don't necessarily mean better absorption due to hepcidin regulation 3
- Gastrointestinal side effects (nausea, constipation, diarrhea) are dose-dependent and may lead to poor compliance 1, 5
- Consider alternate-day dosing or lower doses if side effects occur 4, 3
Low-dose iron supplements containing 20mg of elemental iron can be an effective option for many patients with iron deficiency, particularly those who experience side effects with traditional higher doses.