What ointment is recommended for treating a sty (hordeolum)?

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Treatment of Stys (Hordeolum)

For stys (hordeolum), mupirocin 2% topical ointment is the recommended first-line treatment, applied to the affected eyelid 1-3 times daily. 1

Treatment Approach

  • Warm compresses should be applied to the affected eyelid as a first-line treatment to help promote drainage of the sty 2, 3
  • Mupirocin 2% topical ointment should be applied to the affected area 1-3 times daily after cleaning the area 1, 4
  • Treatment should continue until the sty resolves, typically within 5-10 days 1
  • The affected area may be covered with a sterile bandage after application of the ointment 4

Special Populations

  • For children under 2 years of age, consult a doctor before applying any topical antibiotic ointment 4
  • For children with minor skin infections including stys, mupirocin 2% topical ointment is specifically recommended by clinical guidelines 1, 5
  • For adults and children 2 years and older, apply a small amount (equal to the surface area of the fingertip) to the affected area 1-3 times daily 4

Alternative Treatment Options

  • Triple antibiotic ointment containing bacitracin zinc, neomycin sulfate, and polymyxin B sulfate may be used as an alternative 4
  • For persistent or severe stys, systemic antibiotics may be considered if there are signs of surrounding cellulitis or systemic illness 1
  • Clindamycin is recommended as first-line systemic therapy for complicated skin infections if needed 5

Prevention of Recurrence

  • Maintain good personal hygiene with regular hand washing with soap and water or alcohol-based hand gel 1
  • Avoid reusing or sharing personal items that have contacted infected skin (e.g., towels, washcloths) 1
  • For recurrent stys, consider a 5-10 day course of nasal decolonization with mupirocin twice daily 1
  • Focus cleaning efforts on high-touch surfaces to prevent reinfection 1

When to Seek Further Medical Care

  • If the sty does not improve within 48-72 hours of treatment 5
  • If there are signs of spreading infection (increasing redness, swelling, pain) 1
  • If there are signs of systemic illness (fever, malaise) 1
  • If vision is affected or there is significant pain 2, 3

Common Pitfalls and Caveats

  • Avoid squeezing or attempting to pop the sty, as this may spread the infection 2
  • Tetracycline antibiotics should not be used in children under 8 years of age if systemic treatment is needed 1
  • Cultures from purulent skin infections are recommended if there is no response to initial treatment or if there are signs of systemic illness 1
  • Stys may recur or develop into chalazions if not properly treated 2, 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Non-surgical interventions for acute internal hordeolum.

The Cochrane database of systematic reviews, 2017

Research

Interventions for acute internal hordeolum.

The Cochrane database of systematic reviews, 2013

Guideline

Management of Recurrent Staph Skin Infections in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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