Can I use hydrocolloid (hydrocolloid) dressing for the donor site of a skin graft?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: November 2, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Hydrocolloid Dressing for Skin Graft Donor Sites

Yes, hydrocolloid dressings are an effective and appropriate option for skin graft donor sites, offering advantages in pain reduction and comparable or superior healing outcomes compared to traditional dressings like petrolatum gauze. 1, 2

Evidence Supporting Hydrocolloid Use

Healing Outcomes

  • Hydrocolloid dressings demonstrate effective healing rates for split-thickness skin graft donor sites, with studies showing complete epithelialization comparable to or better than traditional dressings 1, 3, 2
  • One study found significantly shorter treatment duration with hydrocolloid dressings (8.32 ± 1.82 days) compared to bolster dressing and splinting (13.55 ± 5.30 days, p<.001) 1
  • A burn study showed faster healing with hydrocolloid (Dermasorb) compared to Jelonet, with statistically significant differences 2

Pain Management

  • Hydrocolloid dressings provide superior pain control compared to traditional gauze dressings 3, 4, 2
  • Pain scores were significantly lower (0.53 grade) with hydrocolloid compared to xeroform (2.41, p<0.05) 3
  • Patients experienced less donor site discomfort, particularly in the first 3 postoperative days (p=0.003,0.03, and 0.04 for days 1-3 respectively) 4
  • Pain reduction is particularly notable with larger donor site surface areas 4

Practical Advantages

  • Hydrocolloid dressings provide stable immobilization and compression of the graft site without the bulk of traditional methods 1
  • They are flexible, elastic, and adhere well to skin, avoiding complications like abrasion, maceration, and circulatory insufficiency associated with bulky dressings 1
  • The moist wound environment provided by hydrocolloids facilitates reepithelialization 4

Complication Rates

  • Lower complication rates have been reported with hydrocolloid dressings: one case of stitch abscess versus eight cases of partial skin loss with bolster and splinting 1
  • No significant differences in infection rates between hydrocolloid and traditional dressings in most studies 3, 2
  • Both investigators and patients preferred hydrocolloid dressings in comparative trials 2

Cost Considerations

While hydrocolloid dressings are more expensive than traditional xeroform ($54.88 vs $1.16 per patient), they offer better pain control and potentially shorter healing times, which may offset costs through reduced nursing time and patient satisfaction 3

Application Recommendations

  • Apply hydrocolloid dressing directly to the donor site following standard wound preparation 1
  • Change dressings according to manufacturer protocols, typically at 7-day intervals unless soiled or loose 3
  • Monitor for signs of infection, though rates are comparable to traditional dressings 2
  • Ensure adequate coverage and adherence to maintain immobilization and compression 1

References

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.