Wake Forest University and NPWT Development
The provided evidence does not identify Wake Forest University as a key institution in the development of Negative Pressure Wound Therapy (NPWT).
Historical Context of NPWT Development
The available literature indicates that NPWT was introduced into clinical practice in the early 1990s, with the initial commercial vacuum-assisted closure device becoming available in 1995 1, 2. However, none of the guideline or research evidence provided mentions Wake Forest University's involvement in this development.
What the Evidence Shows
The systematic reviews and guidelines examined cover:
- Clinical applications spanning from 1990 to 2013, including over 1000 peer-reviewed publications on NPWT usage 1, 3
- Device evolution from the initial commercial systems through modern portable units with advanced features 2
- International consensus development involving global expert panels of 22 expert surgeons from different surgical disciplines 4, 3
None of these sources attribute the development or key advancement of NPWT to Wake Forest University 4, 1, 2, 3.
Current Evidence Base
The literature focuses on:
- Clinical effectiveness in various wound types including chronic wounds, open abdomen management, and necrotizing infections 4
- Methodological optimization of pressure settings, wound fillers, and treatment protocols 5, 6
- Evidence-based recommendations developed through systematic reviews and international expert consensus 4, 3
The institutional origins of NPWT technology are not documented in the available clinical guidelines and research evidence provided.