What is the recommended dosage of creatine (Creatine Monohydrate) supplement for bulking?

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Creatine Monohydrate Dosing for Bulking

For bulking purposes, use a loading phase of 20 g/day divided into four 5-gram doses for 5-7 days, followed by a maintenance dose of 3-5 g/day as a single daily dose. 1

Loading Phase Protocol

  • Administer 20 g/day divided into four equal 5-gram doses for 5-7 days to rapidly saturate muscle creatine stores 1
  • This loading protocol increases total muscle creatine content (both free creatine and phosphocreatine) and provides the foundation for performance enhancement 2
  • Expect a body mass increase of 1-2 kg during this phase due to intracellular water retention, which contributes to the bulking effect 1

Maintenance Phase Protocol

  • Continue with 3-5 g/day as a single dose for the entire supplementation period after completing the loading phase 1
  • This maintenance dosing preserves elevated muscle creatine stores without requiring continued high-dose administration 3
  • The loading phase is not strictly necessary—you can achieve similar muscle creatine saturation with 3-5 g/day alone, though it takes approximately 3-4 weeks longer 3

Optimization Strategy for Maximum Muscle Gain

  • Consume creatine with approximately 50 g of protein and carbohydrate together to stimulate insulin release and enhance creatine transport into muscle cells 1
  • This co-ingestion strategy maximizes muscle creatine uptake and supports the anabolic environment needed for bulking 1

Important Caveats

  • Use creatine monohydrate specifically—this is the most extensively studied form, while other variants like creatine ethyl ester have not demonstrated superior benefits 3
  • Creatine supplementation appears safe at recommended doses (≤3 g/day maintenance) in healthy adults, though individuals with pre-existing renal disease or those taking nephrotoxic medications should avoid it 4
  • Muscle creatine levels return to baseline approximately 4-6 weeks after stopping supplementation 1
  • The primary mechanism supporting bulking is enhanced performance in high-intensity, short-duration resistance exercises that rely on the ATP-phosphocreatine system, allowing for greater training volume and subsequent muscle hypertrophy 2, 3

References

Guideline

Creatine Monohydrate Supplementation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Creatine: a review of efficacy and safety.

Journal of the American Pharmaceutical Association (Washington, D.C. : 1996), 1999

Research

Creatine supplementation.

Current sports medicine reports, 2013

Research

Effects of creatine supplementation on renal function.

Journal of herbal pharmacotherapy, 2004

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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