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Lumbar Radiculopathy (L5 Nerve Root)

This patient has L5 radiculopathy secondary to L5-S1 disc herniation with lateral recess and foraminal stenosis, confirmed by the constellation of clinical findings (grade I gastrocnemius weakness, absent Achilles reflex, positive straight leg raise) that correlate directly with MRI evidence of nerve root compression. 1

Clinical Diagnostic Features

The diagnosis of lumbar radiculopathy is established through specific clinical and radiographic correlation 2:

  • Radiculopathy is defined as dysfunction of a nerve root associated with pain, sensory impairment, weakness, or diminished deep tendon reflexes in a nerve root distribution 2
  • Sciatica (pain radiating down the leg below the knee in sciatic nerve distribution) is the most common symptom of lumbar radiculopathy, suggesting nerve root compromise from mechanical pressure or inflammation 2
  • The positive straight-leg-raise test (reproduction of sciatica when leg raised between 30-70 degrees) indicates nerve root tension and is a specific indicator of nerve root compression 2, 1

Specific L5 Nerve Root Findings

This patient's presentation is classic for L5 radiculopathy 3, 4:

  • Motor deficit: Grade I weakness of gastrocnemius muscle (ankle plantar flexion weakness) 1
  • Reflex changes: Absent Achilles reflex 1
  • Functional impairment: Ambulating with a limp due to motor weakness 1
  • Pain distribution: Radiating symptoms consistent with L5 nerve root distribution 4

Radiographic Correlation

The MRI findings directly support the clinical diagnosis 1:

  • 6 mm left and central disc herniation at L5-S1 level 1
  • Lateral recess stenosis causing nerve root compression 1
  • Foraminal stenosis at the corresponding level where L5 nerve root exits 1
  • The American College of Radiology emphasizes that MRI findings showing nerve root compression at the corresponding level must correlate with clinical symptoms and neurological deficits 1

Diagnostic Pitfalls to Avoid

Critical consideration: While disc herniations typically cause symptoms at the adjacent level, non-adjacent radiculopathy can occasionally occur 5, 6:

  • An L2/3 disc herniation can rarely cause L5 radiculopathy through atypical mechanisms 5
  • Contralateral radiculopathy from ipsilateral disc herniation may occur due to migrated epidural fat 6
  • However, in this case, the L5-S1 disc herniation with lateral recess and foraminal stenosis at the same level makes this the straightforward diagnosis 1

Exclusion of Alternative Diagnoses

Before confirming lumbar radiculopathy, the following must be excluded 2:

  • Spinal stenosis (narrowing of spinal canal causing neurogenic claudication - leg pain with walking/standing, relieved by sitting) 2
  • Cauda equina syndrome (urinary retention/incontinence, bilateral motor weakness, saddle anesthesia) - this is a surgical emergency 2
  • Cervical or lumbar degenerative disease with nerve root compression at other levels 2
  • Peripheral neuropathy (such as diabetic neuropathy, which would show symmetric distal findings rather than dermatomal distribution) 2
  • Vascular claudication (distinguished from neurogenic claudication by relief with standing still rather than requiring sitting/flexion) 2

Duration and Conservative Treatment Failure

The one-year symptom duration with failed conservative management supports the diagnosis and indicates appropriateness for surgical consideration 1:

  • Symptoms exceeding 6 weeks with objective neurological deficits warrant consideration of surgical intervention 1
  • This patient has tried multiple conservative treatments (chiropractic care, home exercise, medication) without improvement 1
  • The American College of Physicians recommends patients try conservative treatments before surgical intervention, which has been satisfied in this case 1

Diagnostic Confirmation

The diagnosis is definitively established by the triad of 1, 4:

  1. Clinical symptoms: Radicular pain pattern with functional impairment
  2. Objective neurological deficits: Motor weakness (grade I gastrocnemius) and reflex loss (absent Achilles)
  3. Radiographic correlation: MRI showing disc herniation with nerve root compression at the exact level corresponding to clinical findings

References

Guideline

Lumbar Disk Surgery Medical Necessity Assessment

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

The clinical diagnosis of lumbar radiculopathy.

Seminars in ultrasound, CT, and MR, 1993

Research

An L2/3 Disc Herniation-Related L5 Radiculopathy.

Current health sciences journal, 2023

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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