Treatment of Scaly Circular Patches on Skin
For scaly circular patches on the skin, start with topical antifungal therapy (terbinafine cream applied twice daily for 1-2 weeks) if ringworm (tinea corporis) is suspected, or high-potency topical corticosteroids (clobetasol 0.05% or fluocinonide 0.05% cream/ointment) if psoriasis is the diagnosis. 1, 2
Differential Diagnosis Considerations
The clinical presentation of scaly circular patches requires distinguishing between several key conditions:
- Ringworm (Tinea Corporis): Presents as circular, scaly patches with raised borders and central clearing 1
- Psoriasis: Characterized by well-demarcated, erythematous plaques with silvery scale, though circular patterns can occur 2, 3
- Granuloma Annulare: Smooth, annular plaques that may mimic other conditions 4
- Actinic Keratosis: Discrete patches of erythema and scaling on sun-exposed skin, though typically not perfectly circular 2, 5
Treatment Algorithm
If Ringworm (Tinea Corporis) is Suspected:
First-Line Topical Antifungal Treatment:
- Apply terbinafine cream twice daily (morning and night) for 1 week for most cases 1
- Wash affected skin with soap and water and dry completely before applying 1
- Wash hands after each use 1
If Psoriasis is Diagnosed:
Mild Disease (localized plaques):
- High-potency topical corticosteroids: clobetasol 0.05% or fluocinonide 0.05% cream/ointment applied twice daily 2
- Topical vitamin D analogues can be added for enhanced efficacy 2
- Consider cream/lotion/ointment formulations for body lesions 2
Moderate Disease (3-10% body surface area):
- Continue high-potency topical steroids 2
- Add narrow-band UVB phototherapy if available 2
- Consider apremilast or acitretin (if no childbearing potential) 2
Severe or Refractory Disease:
- Systemic therapies including methotrexate, cyclosporine, or biologic agents (adalimumab, ustekinumab, secukinumab, ixekizumab) 2, 6, 3
- Refer to dermatology for consideration of biologics 2
Critical Clinical Pearls
When to suspect fungal infection:
- Circular pattern with raised, scaly border and central clearing 1
- Single or few lesions rather than widespread distribution
- History of contact with infected individuals or animals
When to suspect psoriasis:
- Multiple well-demarcated plaques with thick, silvery scale 2
- Involvement of typical sites: elbows, knees, scalp, presacral region 2, 7
- Family history of psoriasis 3
- Associated nail changes (pitting, oil spots, onycholysis) 7
Red flags requiring dermatology referral:
- Failure to respond to standard first-line treatments 2
- Diagnostic uncertainty between conditions 4
- Extensive disease or immunosuppressed patients 2
- Concern for malignancy (bleeding, pain, significant thickness) 2
Common Pitfalls to Avoid
- Do not use topical corticosteroids for fungal infections, as this will worsen the condition and may lead to tinea incognito 2
- Avoid greasy creams in intertriginous areas, as they may facilitate secondary infections 8
- Use topical steroids cautiously and for short durations to prevent skin atrophy and perioral dermatitis 8
- Consider skin biopsy when clinical presentation is atypical or diagnosis remains uncertain after initial treatment trial 4
Special Populations
Children under 12 years:
- Consult a physician before using antifungal therapy 1
- Topical treatments are generally preferred over systemic agents 3
Immunosuppressed patients: