Does flaxseed lower Lipoprotein(a) (Lp(a))?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Flaxseed has been shown to lower Lipoprotein(a) (Lp(a)) levels, with a significant decrease in plasma Lp(a) levels observed in a meta-analysis of randomized controlled trials. The most recent and highest quality study, a meta-analysis published in 2021 1, found a significant decrease in plasma Lp(a) levels, with a standardized mean difference of -0.22, indicating a modest but significant reduction in Lp(a) levels.

Key Findings

  • The study found that flaxseed supplementation reduced plasma Lp(a) levels by approximately 14-17% in some individuals 1, 2.
  • The potential Lp(a)-lowering effect of flaxseed is likely due to its high content of alpha-linolenic acid (an omega-3 fatty acid), lignans, and soluble fiber, which collectively may influence lipoprotein metabolism 3, 4.
  • For best results, using freshly ground flaxseed rather than whole seeds or oil is recommended, as the ground form provides better bioavailability of beneficial compounds 5.

Recommendations

  • Consuming 30-50 grams of ground flaxseed daily may help lower Lp(a) levels, although individual results may vary 1, 2.
  • Incorporating flaxseed into foods like yogurt, oatmeal, or smoothies can be a convenient and effective way to increase consumption 1.
  • Flaxseed should be considered as part of a broader approach to reducing Lp(a) levels, including other dietary changes, exercise, and possibly medication as recommended by a healthcare provider 1, 4.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.