What is the cause of a white bump inside the eyelid, also known as a (chalazion) or (meibomian cyst)?

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Differential Diagnosis for White Bump Inside Eyelid

  • Single Most Likely Diagnosis
    • Chalazion: A common, benign condition characterized by a small, usually painless, lump or bump on the eyelid due to a blocked oil gland. The justification for this being the most likely diagnosis is its high prevalence and the typical presentation of a white bump inside the eyelid.
  • Other Likely Diagnoses
    • Stye (Hordeolum): An acute, localized infection or inflammation of the eyelid margin involving hair follicles of the eyelashes (external hordeolum) or meibomian glands (internal hordeolum). It presents as a painful, red bump and can appear white if it becomes abscessed.
    • Meibomian Cyst: Similar to a chalazion but often larger and can be more chronic. It's a retention cyst of the meibomian gland and can present as a white or translucent bump.
    • Xanthelasma: A condition characterized by small, yellowish patches or bumps on the eyelids due to accumulation of fat, but can sometimes appear white. It's more common in individuals with high cholesterol.
  • Do Not Miss Diagnoses
    • Basal Cell Carcinoma: Although less common, basal cell carcinoma can present as a bump on the eyelid. Given its potential for malignancy, it's crucial not to miss this diagnosis, despite its lower likelihood.
    • Squamous Cell Carcinoma: Another form of skin cancer that can appear on the eyelid, presenting as a bump or lesion. Early detection is key for effective treatment.
  • Rare Diagnoses
    • Sebaceous Cell Carcinoma: A rare, aggressive form of cancer that originates in the oil glands of the eyelid. It can masquerade as a benign condition like a chalazion or stye, making it important to consider in the differential diagnosis.
    • Kaposi’s Sarcoma: A rare cancer that can cause lesions on the skin, including the eyelids, especially in immunocompromised individuals.
    • Sjögren’s Syndrome: An autoimmune disorder that can cause dry eyes and potentially lead to bumps or lesions on the eyelids due to inflammation or secondary infections.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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