Components of Good Antenatal Care
Good antenatal care should include comprehensive preconception counseling, risk-stratified visit schedules (8-15 visits depending on risk level), systematic screening for medical and psychosocial conditions, targeted interventions including aspirin prophylaxis for preeclampsia prevention, fetal surveillance, and patient education—all delivered through a structured, evidence-based approach rather than ritualistic protocols. 1, 2
Preconception and Early Pregnancy Care (Before 16 Weeks)
Preconception counseling is critical and should not be delayed, as organogenesis begins before many women have their first prenatal visit. 3
- Folic acid supplementation (400-800 mcg daily) must be started before conception to prevent neural tube defects, as neural tube closure occurs at 6 weeks gestation (28 days after conception). 3, 1
- Medication review to identify and discontinue teratogenic agents including ACE inhibitors, ARBs, statins, isotretinoin, warfarin, and certain antiseizure medications. 3, 1
- Optimize chronic conditions before conception, particularly diabetes (target A1C <6.5%), hypertension, and thyroid disorders. 3, 1
- Genetic and carrier screening based on family history, ethnic background, and maternal age, including cystic fibrosis screening as indicated. 3
- Infectious disease screening including HIV, syphilis, hepatitis B, gonorrhea, chlamydia, and rubella immunity status. 3, 2
- Immunization updates with hepatitis B, rubella, varicella, Tdap, HPV, and influenza vaccines as needed. 3
- Low-dose aspirin (81-150 mg daily) initiated before 16 weeks for women with preeclampsia risk factors including prior preeclampsia, chronic hypertension, pregestational diabetes, BMI >30, chronic kidney disease, or antiphospholipid syndrome. 1
- Calcium supplementation (1200 mg daily) if dietary intake is inadequate. 1
Visit Schedule and Frequency
The traditional U.S. schedule of 12-14 visits originated in 1930 without supporting evidence and has remained largely unchanged despite technological advances. 3
- For low-risk women: Evidence supports reduced visit schedules of 8-9 visits with equivalent maternal and neonatal outcomes compared to 12-14 visits. 3
- WHO recommends a minimum of 8 antenatal contacts with midwife-led continuity of care. 1
- International variation ranges from 7.5 visits (France, Netherlands) to 15 visits (Japan), with most peer countries recommending fewer visits than the U.S. 3
- Visit intervals should be monthly until 28 weeks, biweekly until 36 weeks, then weekly until delivery for standard-risk pregnancies, though this can be modified based on individual risk assessment. 3
Second Trimester Care (14-28 Weeks)
- Detailed fetal anatomy ultrasound to screen for structural anomalies. 3, 1
- Fetal echocardiogram for women with pregestational diabetes due to increased risk of cardiac anomalies. 3, 1
- Continue aspirin prophylaxis for preeclampsia prevention through delivery. 1
- Screening for gestational diabetes using oral glucose tolerance test, though timing and universal application remain somewhat controversial across guidelines. 4
- Dilated eye examination for women with preexisting diabetes to monitor for diabetic retinopathy. 3, 1
Third Trimester Care (28 Weeks to Delivery)
- Antepartum fetal surveillance beginning at 32-34 weeks for high-risk pregnancies including pregestational diabetes, using nonstress tests, amniotic fluid assessment, or biophysical profiles. 3, 1
- Preeclampsia monitoring with blood pressure and proteinuria screening, particularly in women with risk factors. 1, 2
- Fetal growth assessment via ultrasound, though routine symphysis-fundal height measurement remains controversial. 4
- Anemia screening around 30 weeks gestation, noting that high hemoglobin is a danger signal rather than reassurance. 5
- Group B Streptococcus screening at 35-37 weeks. 2
Essential Screening and Management Components
Infectious Disease Prevention and Management (apply based on population burden):
- Syphilis screening and treatment is inexpensive and cost-effective. 5
- Urine culture or dipstick for leucocyte esterase and nitrite with treatment of positive cases reduces pyelonephritis risk. 5
- HIV, tuberculosis, malaria, and tetanus prevention and screening as indicated by local epidemiology. 2
Medical Condition Screening:
- Anemia assessment with hemoglobin determination, particularly important around 30 weeks; routine iron supplementation not necessary in well-nourished populations but essential in areas of high anemia prevalence. 5, 2
- Gestational diabetes screening though optimal timing and universal application debated. 4
- Thyroid function screening for women with preexisting thyroid disease or risk factors. 3
Psychosocial Assessment:
- Mental health screening for depression and anxiety using validated tools. 3, 2
- Intimate partner violence screening and appropriate referral. 2
- Substance use assessment including tobacco, alcohol, and drugs using CAGE or T-ACE questionnaires. 3
- Social determinants including housing insecurity, though this is commonly omitted from guidelines. 3
Patient Education and Counseling
- Nutrition counseling assessing anthropometric factors (BMI), biochemical factors (anemia), clinical factors, and dietary risks. 3, 2
- Birth preparedness including recognition of danger signs and when to seek care. 2
- Breastfeeding promotion and infant safe sleep practices. 3
- Family planning for interpregnancy interval optimization. 2
- Avoidance of teratogens including alcohol, tobacco, certain fish with high mercury content, and workplace/environmental toxins. 3
Care Delivery Models
- Provider type: Most peer countries recommend general practitioners or midwives as primary maternity care providers for low-risk women, while U.S. guidelines offer choice between obstetrician-gynecologists, general practitioners, or midwives. 3
- Telemedicine and hybrid models have demonstrated feasibility and acceptability, particularly since the COVID-19 pandemic forced reconsideration of traditional visit schedules. 3
- Risk stratification is essential—care should be tailored based on individual risk factors rather than applying a one-size-fits-all approach. 3
Common Pitfalls to Avoid
- Failing to initiate aspirin prophylaxis before 16 weeks in women with preeclampsia risk factors, missing the critical window for prevention. 1
- Delaying preconception care until just before attempting pregnancy, when organogenesis may already be underway. 3, 6
- Ritualistic adherence to the 1930 visit schedule without evidence-based risk stratification, leading to unnecessary visits for low-risk women and potentially inadequate care for high-risk women. 3
- Overlooking psychosocial factors including mental health, intimate partner violence, and social determinants of health. 3, 2
- Inadequate patient education about danger signs, birth preparedness, and self-care, leading to poor patient satisfaction despite frequent visits. 3, 2
- Missing the late pregnancy anemia screen around 30 weeks, which is more clinically significant than early pregnancy screening. 5