What are the treatment options for Hyperhidrosis (excessive sweating) during pregnancy?

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Last updated: March 28, 2025View editorial policy

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From the Research

Hyperhidrosis during pregnancy can be managed with several safe approaches, prioritizing non-medication strategies and careful use of clinical-strength antiperspirants, with iontophoresis considered for more severe cases, as recommended by the most recent and relevant guidelines 1. The management of hyperhidrosis during pregnancy involves a range of options, from non-medication strategies to more invasive treatments. Non-medication approaches include wearing loose, breathable clothing, using absorbent powders, and avoiding triggers such as spicy foods and caffeine.

  • Clinical-strength antiperspirants containing aluminum chloride (like Certain Dri or Drysol) can be applied at night to dry areas, though use them sparingly and avoid broken skin, as they are considered first-line therapy for patients with mild-to-moderate hyperhidrosis 2, 3.
  • For more severe cases, consulting an obstetrician about prescription options like glycopyrrolate wipes (Qbrexza) may be necessary, which may be considered when benefits outweigh risks.
  • Iontophoresis, which uses a mild electrical current through water to temporarily block sweat glands, is generally considered safe during pregnancy and can be an effective treatment for hyperhidrosis of the palms and soles 1.
  • It is essential to avoid oral anticholinergics, botulinum toxin injections, and miraDry treatments until after pregnancy and breastfeeding, due to potential risks to the fetus or mother.
  • Hyperhidrosis often improves after delivery as hormone levels normalize, and these increased sweat levels during pregnancy result from hormonal changes, increased blood volume, and higher metabolic rate, which collectively raise body temperature and trigger the body's cooling mechanism through sweating.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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