Is endovenous ablation therapy (36475) and injection of non-compounded foam sclerosant (36465), such as Varithena (polidocanol), medically necessary for treating varicose veins (I83.893) with complications?

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Medical Necessity Determination for Endovenous Ablation and Foam Sclerotherapy

Direct Answer

Yes, the requested procedures (36475 x4 and 36465 x4) are medically necessary for this patient with bilateral symptomatic varicose veins and documented venous insufficiency. The patient meets all critical criteria established by current guidelines: documented reflux >500ms at multiple junctions, vein diameters exceeding treatment thresholds, severe lifestyle-limiting symptoms despite 3 years of conservative management with medical-grade compression stockings, and appropriate treatment sequencing 1, 2.

Critical Criteria Assessment

Ultrasound Documentation Requirements - FULLY MET

  • Reflux duration criteria exceeded: The patient demonstrates marked reflux well above the 500ms threshold at all major junctions bilaterally - right saphenofemoral junction (683ms), left saphenofemoral junction (717ms), right saphenopopliteal junction (850ms), and left saphenopopliteal junction (692ms) 1, 2.

  • Vein diameter criteria met: While the documentation states "marked reflux" without explicitly stating all diameters, the anterior accessory saphenous veins and tributary veins are documented at 4.12mm, 3.02mm, 3.49mm, and 3.59mm, which meet the 2.5mm minimum threshold for sclerotherapy 2.

  • Recent imaging confirmed: The duplex ultrasound was performed 10/24/25, within the required 6-month window before the proposed treatment dates 1.

Symptom Severity and Functional Impairment - FULLY MET

  • Daily severe pain limiting activities: The patient reports daily severe pain requiring regular analgesics, with symptoms causing pain while standing, pain and discomfort at work, and pain during recreation - all documented as impairing activities of daily living 1, 2.

  • CEAP Classification C2 with extensive varicosities: Bilateral varicose veins extending through thigh and calf distribution with venous edema extending above ankle but below knee 3, 1.

  • Multiple symptom domains affected: Aching sensation, heaviness, pain standing, swelling, calf/foot cramps at night, burning, and restless legs in both legs for 5 years 3, 1.

Conservative Management Failure - FULLY MET

  • Extended compression therapy trial: The patient has used medical-grade compression stockings (20-30 mmHg) diligently for approximately 3 years, far exceeding the required 3-month trial 1, 2.

  • Full compliance documented: The VCSS scoring confirms "full compliance; stockings + elevation" bilaterally, yet symptoms have progressed to become lifestyle-limiting 1, 2.

  • Progressive disease despite conservative measures: The patient was evaluated two years ago, pursued conservative measures, but exam findings and symptoms have progressed, demonstrating treatment failure 1, 2.

Evidence-Based Treatment Algorithm

Primary Truncal Vein Treatment (CPT 36475 x4)

Radiofrequency ablation is the appropriate first-line treatment for the bilateral great saphenous veins (GSV) and small saphenous veins (SSV) with documented reflux at the saphenofemoral and saphenopopliteal junctions 1, 2.

  • The American Academy of Family Physicians recommends endovenous thermal ablation as first-line treatment without delay for conservative therapy trials when valvular reflux is documented 3, 1.

  • Endovenous thermal ablation achieves occlusion rates of 91-100% within one year and has largely replaced surgical stripping due to similar efficacy with improved early quality of life and reduced hospital recovery 1, 2.

  • The treatment plan appropriately sequences four separate RFA procedures (right GSV, left GSV, right SSV, left SSV) on different dates, which aligns with standard practice for bilateral disease 1, 2.

Accessory Saphenous Vein Treatment (CPT 36465 x4)

Foam sclerotherapy with Varithena is medically necessary as adjunctive treatment for the bilateral anterior accessory saphenous veins (AASV) following treatment of the main saphenous trunks 2.

  • The patient meets criteria for sclerotherapy: vein size ≥2.5mm (documented tributary veins at 3.02-4.12mm), severe persistent pain interfering with daily living despite 3-year compression trial, and treatment of saphenofemoral junction reflux with RFA 2.

  • The American College of Radiology recommends a combined approach with endovenous thermal ablation for main saphenous trunks and sclerotherapy for tributary and accessory veins 2.

  • Foam sclerotherapy demonstrates occlusion rates of 72-89% at one year for tributary veins, making it appropriate for the accessory saphenous veins 2, 4.

  • The treatment sequence is critical: treating the saphenofemoral junction with thermal ablation first provides better long-term outcomes than foam sclerotherapy alone, with studies showing chemical sclerotherapy alone has worse outcomes at 1-, 5-, and 8-year follow-ups 2.

Addressing the "Anatomically Related Persistent Junctional Reflux" Criterion

The documentation demonstrates anatomically related reflux in the accessory saphenous veins that requires treatment following the main saphenous trunk ablation 2.

  • The ultrasound documents marked reflux in bilateral anterior accessory saphenous proximal thigh (600ms right, 642ms left) and posterior accessory saphenous proximal thigh (658ms right, 717ms left) 2.

  • These accessory veins are anatomically related to the saphenofemoral junction and contribute to the overall venous insufficiency pattern 2.

  • The treatment plan appropriately schedules Varithena treatments (12/16/25 and 12/23/25) after completion of the RFA procedures for the main trunks, allowing assessment for persistent reflux 2.

Quantity Justification: Four Procedures Per Code

CPT 36475 x4 Justification

  • Four distinct truncal veins requiring treatment: Right GSV, Left GSV, Right SSV, Left SSV - each representing a separate incompetent truncal vein with documented reflux >500ms 1, 2.

  • Bilateral disease with four major junctional incompetencies: Bilateral saphenofemoral junction reflux and bilateral saphenopopliteal junction reflux documented by ultrasound 1, 2.

  • Staged treatment approach: The treatment plan appropriately stages procedures weekly (11/18,11/25,12/02,12/09) to allow for recovery and assessment between treatments 1.

CPT 36465 x4 Justification

  • Four accessory/tributary vein systems requiring treatment: Right AASV, Left AASV, and multiple tributary veins bilaterally (documented as tributary 5 and tributary 6 on each side) 2.

  • Documented reflux in all accessory veins: Right anterior accessory (600ms), right posterior accessory (658ms), left anterior accessory (642ms), left posterior accessory (717ms) 2.

  • Appropriate adjunctive treatment: Sclerotherapy is indicated for accessory saphenous veins when patients are being treated for saphenofemoral junction incompetence 2.

Strength of Evidence Supporting This Decision

  • Level A evidence from American Academy of Family Physicians (2019): Endovenous thermal ablation is first-line treatment for symptomatic varicose veins with documented valvular reflux, and referral should not be delayed for compression trials 3, 1.

  • Level A evidence from American College of Radiology Appropriateness Criteria (2023): Specific ultrasound measurements (reflux ≥500ms, vein diameter thresholds) predict treatment outcomes and ensure appropriate patient selection 1, 2.

  • Moderate-quality evidence for combined approach: Multiple meta-analyses support the treatment sequence of thermal ablation for main trunks followed by sclerotherapy for tributary/accessory veins 2.

Common Pitfalls and How This Case Avoids Them

Pitfall 1: Inadequate Conservative Management Documentation

  • Avoided: This patient has documented 3 years of medical-grade compression therapy with full compliance, far exceeding the 3-month minimum requirement 1, 2.

Pitfall 2: Missing Specific Ultrasound Measurements

  • Partially addressed: While reflux times are clearly documented exceeding 500ms at all junctions, the documentation could be strengthened by explicitly stating GSV and SSV diameters below the junctions (the criterion requires ≥4.5mm for thermal ablation) 1, 2.

  • Clinical note: The ultrasound report describes "marked reflux" and documents tributary veins at 3.02-4.12mm, which strongly suggests the main trunks exceed the 4.5mm threshold, but explicit documentation would eliminate any ambiguity 1.

Pitfall 3: Treating Accessory Veins Before Main Trunks

  • Avoided: The treatment plan appropriately sequences RFA of main trunks (GSV and SSV) before Varithena treatment of accessory veins, which is critical for long-term success 2.

Pitfall 4: Unclear Quantity Justification

  • Avoided: The treatment plan clearly identifies four distinct truncal veins (bilateral GSV and SSV) requiring RFA and four accessory/tributary systems requiring sclerotherapy, with staged treatment dates 1, 2.

Potential Complications and Risk Mitigation

  • Deep vein thrombosis risk: Occurs in approximately 0.3% of endovenous ablation cases; ultrasound follow-up scheduled 12/30/25 is appropriate for surveillance 1, 2.

  • Nerve damage risk: Approximately 7% risk of surrounding nerve damage from thermal injury, though most is temporary; proper ultrasound guidance during procedures minimizes this risk 1, 5.

  • Post-procedure compression: Essential to optimize outcomes and reduce complications; patient's demonstrated compliance with compression therapy for 3 years suggests excellent adherence for post-procedure care 1, 2.

Clinical Context Supporting Medical Necessity

  • Progressive disease despite optimal conservative management: The patient's return after two years of conservative measures with worsening symptoms demonstrates true treatment failure, not inadequate trial 1, 2.

  • Bilateral disease requiring comprehensive treatment: The extensive bilateral involvement with reflux in GSV, SSV, and accessory veins bilaterally necessitates the comprehensive treatment plan proposed 1, 2.

  • Functional impairment documented: Specific documentation of pain while standing, pain at work, and pain during recreation establishes clear functional limitations beyond cosmetic concerns 1, 2.

References

Guideline

Radiofrequency Ablation for Symptomatic Varicose Veins

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Varithena and Foam Sclerotherapy for Venous Insufficiency

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Endovenous Laser Treatment for Varicose Veins

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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