What are the guidelines for RDP (Renal Dialysis Protocol) infusion therapy?

RDP Infusion: Clarification Required

I cannot provide specific guidelines for "RDP infusion" as this abbreviation does not correspond to any recognized medical therapy in the provided evidence or standard medical terminology.

Possible Interpretations

The evidence provided relates exclusively to Renal Replacement Therapy (RRT) and peritoneal dialysis, not "RDP." If you are asking about:

Renal Dialysis Protocol (as suggested in the expanded question)

There is no standardized abbreviation "RDP" for renal dialysis in nephrology practice. The correct terminology is:

• RRT (Renal Replacement Therapy) - the umbrella term for all dialysis modalities 1
• CRRT (Continuous Renal Replacement Therapy) - for continuous modalities 1
• PD (Peritoneal Dialysis) - for peritoneal-based therapy 1
• HD (Hemodialysis) - for intermittent hemodialysis 1

If You Mean RRT Infusion Parameters

For continuous RRT (CRRT), deliver an effluent volume of 20-25 mL/kg/hour using bicarbonate-based replacement fluid. 1, 2, 3

Key CRRT parameters include:

• Modality: CVVHDF (continuous venovenous hemodiafiltration) is preferred 2, 3
• Effluent dose: 20-25 mL/kg/hour (not higher doses, as they show no mortality benefit) 1, 2, 3
• Replacement fluid: Bicarbonate-based solutions are recommended over lactate-based 1, 2
• Anticoagulation: Regional citrate anticoagulation is preferred when no contraindications exist 1, 2, 3

If You Mean Peritoneal Dialysis Infusion

For peritoneal dialysis initiation, prescribe four 2-L exchanges per day to achieve a weekly Kt/V of at least 2.0. 1

• Initiation threshold: Start when weekly Kt/V falls below 2.0 or creatinine clearance is 9-14 mL/min/1.73 m² 1
• Dwell times: Standard CAPD uses continuous dwells; APD uses multiple short overnight exchanges 1
• Icodextrin: Use for the long daytime dwell in APD or nighttime dwell in CAPD to optimize ultrafiltration 1

Request for Clarification

Please specify the exact therapy you are asking about by providing:

• The full name of the treatment (not abbreviation)
• The clinical context (acute kidney injury, chronic kidney disease, specific indication)
• Whether you are asking about dialysate composition, infusion rates, or treatment protocols

This will allow me to provide precise, evidence-based guidance from the available nephrology literature.