From the FDA Drug Label
USE • relieves occasional constipation (irregularity) • generally produces a bowel movement in 1 to 3 days The recommended medication for constipation lasting 3 days is polyethylene glycol (PO), as it generally produces a bowel movement in 1 to 3 days 1.
From the Research
For constipation lasting three days, I recommend starting with an over-the-counter osmotic laxative like polyethylene glycol (MiraLAX) at a dose of 17g (one capful) mixed in 8 ounces of water once daily for up to 7 days, as supported by the most recent and highest quality study 2. This approach is based on the latest evidence from a systematic review published in 2021, which found good evidence (grade A recommendation) for the use of polyethylene glycol (PEG) as a first-line laxative for chronic constipation 2.
Key Considerations
- The use of osmotic laxatives like polyethylene glycol is recommended due to their efficacy in softening stool and promoting bowel movements without causing dependence or significant side effects 2.
- If quicker relief is needed, a stimulant laxative such as bisacodyl (Dulcolax) 5-10mg orally can be considered, as it typically works within 6-12 hours 3, 2.
- For immediate relief, options like a glycerin suppository or Fleet enema can work within 15-60 minutes, but these should be used judiciously and not as a first-line treatment due to potential for dependence and side effects.
- It is crucial to increase water intake to at least 8 glasses daily and add more fiber to the diet gradually (aiming for 25-30g daily) to help manage constipation and prevent future episodes 4, 5.
- Regular physical activity is also recommended as it can help stimulate bowel movements and improve overall gastrointestinal health.
Important Warnings
- If constipation persists beyond a week, is accompanied by severe pain, bleeding, or if there is a history of bowel conditions, it is essential to consult a healthcare provider as this could indicate a more serious underlying condition 6.
- The choice of laxative and treatment approach should be individualized based on the patient's specific needs, medical history, and response to treatment, with consideration of the potential for side effects and interactions with other medications.