Can bisacodyl (Dulcolax) and polyethylene glycol (Miralax) be taken in the presence of diverticulitis?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 2, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

It's generally not recommended to take Dulcolax and Miralax together if you have diverticulitis without medical supervision. During an active diverticulitis flare, these laxatives could potentially worsen your condition by increasing intestinal contractions and pressure in the colon. Diverticulitis is an inflammation or infection of small pouches (diverticula) in your digestive tract, and it typically requires treatment with antibiotics, a liquid or low-fiber diet initially, and rest. Laxatives might irritate the inflamed areas and could potentially increase the risk of complications.

Instead of self-medicating, contact your healthcare provider for appropriate treatment of diverticulitis, which may include pain management, antibiotics, and dietary modifications. Once the acute inflammation has resolved, your doctor may recommend gentle stool softeners or fiber supplements to prevent constipation, but this should be part of a supervised treatment plan tailored to your specific condition and medical history. According to the most recent guidelines, such as those from the American Gastroenterological Association 1, the management of diverticulitis involves a comprehensive approach that considers the patient's overall health, lifestyle, and genetic factors.

Some key points to consider:

  • A high-quality diet, regular physical activity, and maintaining a normal body mass index can help reduce the risk of recurrence 1.
  • Avoiding nonsteroidal anti-inflammatory drugs (NSAIDs) and smoking can also help prevent complications 1.
  • Genetic factors play a significant role in determining the risk of diverticulitis, with approximately 50% of the risk attributed to genetic effects 1.
  • There is no evidence to support the use of 5-aminosalicylic acid, probiotics, or rifaximin to prevent recurrent diverticulitis 1.

It's essential to follow the guidance of your healthcare provider and adhere to a supervised treatment plan to manage diverticulitis effectively and prevent potential complications.

From the Research

Medication Interactions with Diverticulitis

  • There is no direct evidence in the provided studies regarding the interaction between Dulcolax (bisacodyl) and Miralax (polyethylene glycol) with diverticulitis 2, 3.
  • However, the studies suggest that patients with diverticulitis should be treated based on the severity of their symptoms and the presence of complications such as abscesses or perforation 2, 3.
  • For constipation, which may be a symptom of diverticulitis, osmotic laxatives like polyethylene glycol (Miralax) are considered safe and effective for treatment 4, 5, 6.
  • Stimulant laxatives like bisacodyl (Dulcolax) may also be used for constipation, but their use should be approached with caution in patients with diverticulitis, as they may exacerbate symptoms in some cases 4, 5.
  • It is essential to consult a healthcare professional for personalized advice on managing diverticulitis and constipation, as the treatment approach may vary depending on individual circumstances 2, 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

The management of diverticulitis: a review of the guidelines.

The Medical journal of Australia, 2019

Research

Evidence-based treatment strategies for acute diverticulitis.

International journal of colorectal disease, 2021

Research

Medical treatment of constipation.

Clinics in colon and rectal surgery, 2005

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.