When to Stop Mammography Screening
There is no specific age to stop mammography screening—continue annual mammograms as long as you remain in overall good health with a life expectancy greater than 10 years and are willing to undergo follow-up testing if abnormalities are found. 1
Key Decision Framework
Base Your Decision on Health Status, Not Age Alone
Life expectancy and comorbidities should guide the decision to stop screening, not chronological age. 1
Mortality benefits from mammography require several years to be fully realized, so screening only benefits women who are likely to live long enough to experience those benefits. 1
Women with moderate to severe comorbid conditions (cardiovascular disease, diabetes, COPD, chronic renal failure, dementia, congestive heart failure) that negatively affect life expectancy are unlikely to benefit from continued screening. 1
Evidence by Age Group
Ages 70-74:
- Observational studies suggest continued benefit from screening in this age group for women in good health. 1
- The estimated benefit is approximately 13 fewer breast cancer deaths per 10,000 women screened over 10 years. 2
- Clinical trial data for this age range are inconclusive, as randomized trials did not enroll women over age 74. 1
Age 75 and Older:
- Women age 75+ may continue to benefit from biennial screening if they have no or low comorbidity and life expectancy exceeds 10 years. 1
- However, one large observational study found no substantial reduction in 8-year breast cancer mortality for women aged 75-84 who continued annual screening compared to those who stopped. 3
- The U.S. Preventive Services Task Force states there is insufficient evidence to assess benefits and harms in women 75 years or older. 1
Practical Assessment of Life Expectancy
Use the 10-year life expectancy threshold as your guide:
Women with less than 10 years of estimated life expectancy should generally stop screening, as potential harms outweigh benefits. 4
For women with greater than 10 years life expectancy, the decision becomes a value judgment weighing potential benefits against harms. 4
Consider using validated life expectancy calculators that incorporate age, functional status, and comorbidities to guide discussions. 4
Important Considerations
Potential Harms Increase with Age:
- Overdiagnosis (detecting cancers that would never become clinically apparent) increases with age at screening. 1
- Over 10 years of continued screening, approximately 200 per 1,000 women will experience false-positive mammograms, and 13 per 1,000 will experience overdiagnosis. 4
Screening Frequency After Age 70:
- If continuing screening, biennial (every 2 years) rather than annual mammography provides a reasonable balance of benefits and harms for most older women. 1, 5
- Annual screening in women over 75 has not demonstrated substantial mortality benefit compared to stopping. 3
Common Pitfalls to Avoid
Don't use age 74 as an automatic cutoff—this arbitrary threshold from clinical trials does not reflect individual health status. 1
Don't continue screening in women with severe comorbidities or limited life expectancy—the harms will outweigh any potential benefit. 1, 4
Don't assume all healthy older women should continue indefinitely—even in healthy women over 75, the evidence for continued benefit is limited. 3