Can a push of glutathione (reduced form of glutamic acid, cysteine, and glycine) 2000 milligrams be administered?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

I strongly advise against self-administering a push of glutathione 2000 mg, as it requires proper medical supervision by a licensed healthcare provider. The typical dose of intravenous glutathione ranges from 600-2400 mg, but this should only be administered by qualified medical professionals in appropriate clinical settings. Glutathione is an antioxidant that helps neutralize free radicals and supports detoxification processes in the body. IV administration bypasses the digestive system where oral glutathione is largely broken down.

Key Considerations

  • According to a recent study 1, supplementing Glycine and N-Acetylcysteine (GlyNAC) in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, physical function, and aging hallmarks.
  • Another study 2 found that GlyNAC supplementation is safe and well-tolerated, and may increase glutathione levels in older adults with high glutathione demand.
  • It is essential to consult with a healthcare provider who can evaluate your medical history, determine if glutathione therapy is appropriate for you, and administer it safely.

Potential Risks

  • Self-administration of IV substances is dangerous and could lead to serious complications including infection, air embolism, or adverse reactions.
  • A study 3 highlighted the importance of proper administration and monitoring of antioxidant supplements to minimize potential side effects.

Recommendations

  • If you're interested in glutathione therapy, consult with a healthcare provider to discuss the potential benefits and risks, and determine the best course of treatment for your individual needs.
  • Consider alternative methods of increasing glutathione levels, such as supplementing with GlyNAC or other antioxidants, under the guidance of a healthcare provider.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.