What is the step-by-step approach to reading an Electrocardiogram (ECG)?

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Last updated: November 12, 2025View editorial policy

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Systematic Approach to ECG Interpretation

Follow a structured, sequential method when reading an ECG, beginning with rate and rhythm assessment, followed by interval measurements, axis determination, and systematic waveform analysis to ensure no critical findings are missed. 1

Step 1: Calculate Heart Rate

  • Determine heart rate by counting the number of large squares (5 mm) between consecutive R waves (300 divided by number of large squares), or count QRS complexes in a 6-second strip and multiply by 10 for irregular rhythms 1
  • Normal heart rate is 60-100 beats per minute 1

Step 2: Assess Rhythm Regularity

  • Examine R-R intervals for consistency by measuring the distance between consecutive R waves across the entire tracing 1
  • Identify the underlying rhythm (sinus, atrial, junctional, or ventricular) based on P wave morphology and its relationship to QRS complexes 1

Step 3: Measure Critical Intervals

  • PR interval: Measure from the beginning of the P wave to the beginning of the QRS complex (normal 120-200 ms or 3-5 small squares) to assess AV conduction 1
  • QRS duration: Measure the width of the QRS complex (normal <120 ms or <3 small squares) to evaluate ventricular conduction 1
  • QT interval: Measure from the beginning of the QRS to the end of the T wave and correct for heart rate (QTc normal <450 ms for men, <460 ms for women) 1

Step 4: Determine Electrical Axis

  • Examine leads I and aVF to quickly determine the axis quadrant: if both are positive, the axis is normal (0° to +90°); if lead I is positive and aVF is negative, there is left axis deviation (-30° to -90°); if lead I is negative and aVF is positive, there is right axis deviation (+90° to +180°) 1
  • Normal axis ranges from -30° to +90° 1

Step 5: Analyze P Wave Morphology

  • Evaluate P wave characteristics: should be upright in leads I, II, and aVF; biphasic in V1; duration <120 ms; amplitude <2.5 mm 1
  • Abnormal P waves suggest atrial enlargement or abnormal atrial conduction 1

Step 6: Examine QRS Complex Morphology

  • Look for pathologic Q waves (>1 mm wide and >1/3 the height of the R wave in the same lead), which suggest prior myocardial infarction 1
  • Assess R wave progression across precordial leads (V1-V6), with R wave amplitude normally increasing from V1 to V4, then decreasing toward V6 1
  • Evaluate for signs of ventricular hypertrophy using voltage criteria 1

Step 7: Evaluate ST Segments

  • Measure ST segment deviation at the J point (junction between QRS and ST segment), looking for elevation or depression that may indicate ischemia, injury, or infarction 1
  • ST elevation >1 mm in two contiguous leads suggests acute myocardial injury 1

Step 8: Analyze T Wave Morphology

  • T waves should normally be upright in leads I, II, and V3-V6; inverted in aVR; and variable in III, aVL, aVF, V1, and V2 1
  • T wave inversions in unexpected leads may indicate ischemia or other pathology 1

Step 9: Look for Additional Features

  • Check for U waves (small deflections after T waves), which may indicate hypokalemia or bradycardia 1
  • Assess for signs of chamber enlargement using P wave abnormalities and QRS voltage criteria 1
  • Identify conduction abnormalities such as bundle branch blocks (QRS >120 ms with specific morphology patterns) 1

Step 10: Verify and Contextualize

  • Always verify computerized ECG interpretations, as automated algorithms can produce erroneous information, particularly for rhythm disturbances, ischemia, or infarction 2, 3
  • Consider patient-specific factors including age, gender (QT intervals are longer in women), medications (antiarrhythmics, psychotropics can alter findings), and clinical presentation 1
  • Compare with previous ECGs to identify new or evolving changes 2

Common Pitfalls to Avoid

  • Inadequate filtering can distort high-frequency components (Q waves, notches) and low-frequency components (ST segments), affecting diagnostic accuracy 2
  • Poor electrode placement and skin preparation create artifacts that may mimic pathology 4
  • Relying solely on computer interpretation without physician over-reading can lead to missed diagnoses with significant medical and legal consequences 2

References

Guideline

ECG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

The Electrocardiogram: Still a Useful Tool in the Primary Care Office.

The Medical clinics of North America, 2019

Research

What is inside the electrocardiograph?

Journal of electrocardiology, 2008

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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