What are the possible causes of patchy hair loss with pruritus?

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Differential Diagnosis for Patchy Hair Loss with Itching

The following conditions can cause patchy hair loss accompanied by itching. It's crucial to approach these symptoms with a broad differential to ensure accurate diagnosis and appropriate treatment.

  • Single Most Likely Diagnosis
    • Alopecia Areata: This is an autoimmune condition that leads to patchy hair loss, often accompanied by itching or burning sensations before the hair falls out. It's a common cause of hair loss and can be treated with corticosteroids, among other treatments. 1
  • Other Likely Diagnoses
    • Tinea Capitis (Ringworm of the Scalp): A fungal infection that causes hair loss, itching, and sometimes redness. It's more common in children but can occur in adults. Treatment involves antifungal medications. 2
    • Psoriasis: While more commonly associated with skin plaques, psoriasis can cause scalp itching and hair loss. Treatment often involves topical corticosteroids, vitamin D analogs, or systemic therapy for more severe cases. 3
    • Seborrheic Dermatitis: This condition causes scaly patches, red skin, and stubborn dandruff, leading to itching and potential hair loss. It's treated with medicated shampoos and topical corticosteroids. 4
  • Do Not Miss Diagnoses
    • Lymphoma: Certain types of lymphoma, particularly cutaneous T-cell lymphoma (CTCL), can present with skin symptoms including itching and hair loss. Early diagnosis is critical for effective treatment. 5
    • Thyroid Disorders: Both hypothyroidism and hyperthyroidism can cause hair loss and itching. These conditions are treatable with thyroid hormone replacement or anti-thyroid medications, respectively. 6
  • Rare Diagnoses
    • Alopecia Monolocularis: A rare condition causing a single patch of hair loss, which might be accompanied by itching.
    • Trichotillomania: A psychological disorder where individuals compulsively pull out their hair, which can lead to patchy hair loss and sometimes itching due to the constant pulling.
    • Discoid Lupus Erythematosus: A chronic skin condition of sores with inflammation and scarring favoring the face, ears, and scalp but can cause hair loss and itching. 7

References: 1 Alopecia Areata. (2022). National Institute of Arthritis and Musculoskeletal and Skin Diseases. 2 Tinea Capitis. (2020). Centers for Disease Control and Prevention. 3 Psoriasis. (2022). American Academy of Dermatology. 4 Seborrheic Dermatitis. (2022). Mayo Clinic. 5 Cutaneous T-Cell Lymphoma. (2022). American Cancer Society. 6 Thyroid Disease and Hair Loss. (2020). Endocrine Society. 7 Discoid Lupus Erythematosus. (2022). Lupus Foundation of America.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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