Management of Clot in Foley Catheter
For a clotted Foley catheter, immediately irrigate forcefully with normal saline using a catheter-tip syringe through the drainage port, and if this fails to restore patency, replace the catheter with a large-bore three-way catheter (22-24 Fr) to enable continuous bladder irrigation and clot evacuation. 1
Immediate Management Algorithm
Step 1: Initial Irrigation Attempt
- Perform forceful manual irrigation with normal saline as the first-line intervention to restore catheter patency 1
- Use a catheter-tip syringe with maximal one-handed pressure through the drainage port (not the irrigation port), as this provides superior flow rates (29-30 mL/s vs 8-9 mL/s) 2
- The minimum flush volume should be twice the catheter volume 1
Step 2: Catheter Replacement if Irrigation Fails
- Replace the existing catheter with a 22-24 Fr three-way Foley catheter if initial irrigation does not clear the clot 2
- The Bardex 22-24 Fr three-way catheters demonstrate superior continuous irrigation flow (1.6-1.7 mL/s) compared to other brands and are optimal for managing clot retention 2
- For severe clot retention unresponsive to standard large-bore catheters, consider using a 28-32 Fr fenestrated rectal tube (Rusch red rubber), which has successfully evacuated clots in 100% of cases where standard catheters failed 3
Step 3: Continuous Bladder Irrigation
- Establish continuous bladder irrigation through the three-way catheter using normal saline 1
- Maintain the irrigation bag 80 cm above the catheter level to optimize gravity flow 2
- Continue irrigation until the drainage is clear for 24 hours 3
Alternative Techniques for Refractory Cases
Hydrogen Peroxide Irrigation
- For difficult-to-remove clots, manual bladder irrigation with hydrogen peroxide solution through a 20 Fr three-way Foley catheter with large-diameter side holes achieved successful clot evacuation in 87% of patients (27/31) 4
- This technique improves efficiency of clot dissolution and evacuation 4
When Conservative Measures Fail
- If clots cannot be evacuated with irrigation techniques, endoscopic intervention in the operating room becomes necessary 3
- Consider cystoscopy the following day to confirm complete clot evacuation if hematuria persists 3
Critical Pitfalls to Avoid
Never use fibrinolytic drugs (urokinase, alteplase) for bladder clots - these are indicated only for catheter lumen thrombosis in central venous catheters, not urinary catheters, and carry greater risk of thrombosis when used inappropriately 1
Do not inflate the balloon during difficult catheterization - this can cause urethral injury and worsen clot formation, particularly in the prostatic urethra 5
Avoid using catheters smaller than 22 Fr for clot management - smaller catheters have inadequate drainage capacity for clot evacuation 2
Underlying Cause Assessment
- Obtain urine culture before initiating antibiotics if infection-related hematuria is suspected 6
- Gross hematuria with clots may indicate bladder injury (present in 77-100% of bladder injuries), particularly in the context of recent catheterization or pelvic trauma 6
- Perform retrograde urethrography before further catheterization attempts if there are signs of urethral injury (blood at meatus, difficulty passing catheter, perineal ecchymosis) 6
Duration of Catheterization
- Maintain catheter drainage until hematuria resolves 6
- For uncomplicated cases after clot evacuation, standard duration is 2-3 weeks, though this may be extended with concurrent injuries 1
- Remove the catheter as soon as clinically appropriate to prevent catheter-associated complications 6