Treatment of Puerperal Mastitis
Continue breastfeeding or milk expression on the affected breast while initiating antibiotics that cover Staphylococcus aureus, specifically dicloxacillin or cephalexin as first-line agents, and drain any abscesses that develop. 1, 2
Immediate Management Priorities
Continue Breastfeeding
- Regular feeding or milk expression from the affected breast is essential and must be encouraged - discontinuing breastfeeding worsens the condition and increases risk of abscess formation 1, 2, 3
- Breastfeeding can safely continue even if an abscess has formed, provided the infant's mouth does not contact purulent drainage from the breast 1, 2
- Complete emptying of the breast reduces risk of progression and is therapeutic 2
- No ill effects occur in infants who continue nursing from the affected breast 3
Antibiotic Therapy
- Start antibiotics effective against Staphylococcus aureus: dicloxacillin or cephalexin are first-line choices 2
- Cephalosporins are appropriate empiric therapy based on expected pathogens 4
- If no improvement occurs within 24 hours of conservative measures, antibiotics must be initiated 4
- Consider methicillin-resistant S. aureus (MRSA) coverage if patient fails initial therapy, as MRSA now accounts for up to 64% of S. aureus isolates in puerperal mastitis 5
- For suspected MRSA, use antibiotics effective against this organism (e.g., trimethoprim-sulfamethoxazole, clindamycin) 5
Pain Management
- Provide appropriate analgesics, as pain control is essential and can prevent symptom exacerbation 1
Management of Complications
Breast Abscess
- Approximately 10% of mastitis cases progress to breast abscess 1, 2
- Abscesses require drainage - either surgical drainage or needle aspiration 2
- Under antibiotic coverage, abscesses can be punctured rather than requiring open surgical drainage in most cases 4
- Surgical intervention with incision and drainage is reserved for cases where needle aspiration fails 4
- Patients requiring incision and drainage typically have longer duration of symptoms before treatment, longer hospitalizations, and higher rates of MRSA infection 5
- Breastfeeding can continue even after abscess drainage, as long as the infant avoids contact with purulent drainage 1, 2
Key Clinical Pitfalls
Timing of Antibiotic Initiation
- Early antibiotic therapy prevents abscess formation 3
- Delaying treatment of non-responsive cases leads to abscess development 1
- The 24-hour window is critical - if conservative measures don't improve symptoms, antibiotics are mandatory 4
Breastfeeding Discontinuation
- Never advise stopping breastfeeding - this is a common error that worsens outcomes 1, 3
- Patients who undergo incision and drainage are more likely to discontinue breastfeeding, but this should be discouraged unless absolutely necessary 5
- Bromocriptine for lactation suppression is not suitable if the mother wishes to continue breastfeeding 4