From the Research
Inositol is generally considered safe during pregnancy when used in appropriate doses, with the most recent and highest quality study suggesting its potential benefits in preventing gestational diabetes mellitus (GDM) and improving maternal and fetal health outcomes 1.
Key Points to Consider
- Inositol exists in two main forms - myo-inositol and D-chiro-inositol - with myo-inositol being the more commonly used form during pregnancy.
- The recommended dose of inositol during pregnancy is typically in the range of 2-4 grams per day, although it is essential to consult with a healthcare provider before starting any supplement.
- Inositol may be particularly beneficial for pregnant women with polycystic ovary syndrome (PCOS) or gestational diabetes, as it can help improve insulin sensitivity and potentially reduce complications.
- Some research suggests that inositol supplementation might lower the risk of gestational diabetes and help maintain healthy blood pressure during pregnancy, as supported by a recent meta-analysis of randomized controlled trials 1.
Mechanism of Action and Benefits
- Inositol works by supporting cellular signaling pathways involved in insulin function and may help regulate hormones.
- The potential benefits of inositol supplementation during pregnancy include improved glycemic control, reduced risk of preterm birth, and lower risk of pregnancy-induced hypertension, as reported in a recent study 1.
Safety and Side Effects
- Side effects of inositol supplementation are generally mild and can include nausea or digestive discomfort.
- Women should start with lower doses and increase gradually to minimize these effects.
- Despite its apparent safety, pregnant women should always discuss inositol supplementation with their healthcare provider before beginning use, as emphasized in a review of inositol and antioxidant supplementation during pregnancy 2.