From the Guidelines
Testosterone therapy for women in injection form typically involves doses ranging from 0.1 to 0.5 ml per dose, with the most common formulations being testosterone cypionate or testosterone enanthate, and the dosage carefully determined by a healthcare provider based on symptoms, hormone levels, and individual response. When considering testosterone replacement therapy for women, it's crucial to select the appropriate formulation and dosage to minimize side effects and maximize benefits. According to the study by Bhasin et al. 1, the typical dose range for testosterone enanthate is 100-200 mg every 2 weeks or 50 mg weekly, and for testosterone cypionate, it is also 100-200 mg every 2 weeks or 50 mg weekly.
Given the concentrations of these formulations (100-200 mg/mL), the volume of the injection would be significantly lower than the concentration, typically in the range of 0.1 to 0.5 ml per dose, depending on the specific dosage prescribed by the healthcare provider. For example, a dose of 10 mg of testosterone enanthate or cypionate would be approximately 0.05 to 0.1 ml, considering the 100 mg/ml concentration.
Key considerations for testosterone therapy in women include:
- Starting with the lowest effective dose to minimize side effects such as acne, hair growth, and potential cardiovascular risks.
- Regular monitoring of testosterone levels to maintain target levels within the upper normal female range (around 30-70 ng/dL).
- Individualization of the dosage through consultation with a healthcare provider experienced in hormone therapy for women.
- Careful selection of the formulation and administration route based on patient preferences, lifestyle, and specific medical needs.
It's essential to consult with a healthcare provider to determine the most appropriate formulation, dosage, and administration schedule for each individual patient, taking into account their unique medical history, symptoms, and laboratory results 1.
From the Research
Testosterone Therapy for Women: Injection Form
- The available evidence does not provide a specific dosage of testosterone therapy for women in injection form, measured in milliliters (ml) 2, 3, 4, 5, 6.
- Testosterone replacement therapy (TRT) has been used for various conditions, including low libido in women, and is available in different formulations, such as intramuscular (IM) injections 4.
- The routes of delivery approved for use in the Western world include buccal, nasal, subdermal, transdermal, and intramuscular (IM) 4.
- However, the specific dosage and volume of testosterone injections for women are not mentioned in the provided studies 2, 3, 4, 5, 6.
- It is essential to note that testosterone therapy should be individualized, and each woman should weigh the risks and benefits, as the long-term safety of testosterone use in women has not been well established 2, 3, 5, 6.