Missed Abortion (Aborto Retenido)
This clinical scenario describes a missed abortion (also termed "embryonic/fetal demise" or "aborto retenido"), defined as embryonic or fetal death without spontaneous expulsion of conception products. 1, 2
Diagnostic Classification
The Society of Radiologists in Ultrasound 2025 consensus guidelines establish that this presentation falls under "Diagnostic of Early Pregnancy Loss (EPL)" with the specific subcategory of embryonic/fetal demise when there is confirmed absence of cardiac activity with retained products of conception. 3 The key diagnostic features include:
- Crown-rump length ≥7 mm without cardiac activity, OR
- Mean sac diameter ≥25 mm without an embryo (anembryonic pregnancy), OR
- Absence of embryo ≥14 days after visualization of gestational sac 3, 2
The term "missed abortion" remains clinically acceptable, though modern terminology favors "embryonic/fetal demise" (with "fetal demise" specifically used at ≥11 weeks gestation). 3, 1 Avoid obsolete terms like "blighted ovum" or "nonviable pregnancy." 3, 4
Critical Management Considerations at 10 Weeks with 8-Week Retention
Active evacuation is mandatory—expectant management is absolutely contraindicated in this scenario. 1 The prolonged retention (8 weeks since fetal death) creates substantial maternal risks:
Immediate Risks Requiring Urgent Intervention
- Intrauterine infection risk increases significantly with time, particularly beyond 18 hours from diagnosis 1, 4
- Coagulopathy risk from retained products 1
- Maternal sepsis from prolonged tissue retention 1
Signs of Infection (Do NOT Wait for Fever)
Clinical symptoms of infection may be less overt at earlier gestational ages—do not delay treatment waiting for fever. 3, 1 Look for:
- Maternal tachycardia
- Purulent cervical discharge
- Fetal tachycardia (if applicable)
- Uterine tenderness 3, 1
If infection is suspected, initiate broad-spectrum antibiotics immediately and proceed with urgent evacuation. 1 Do not delay definitive treatment waiting for amniocentesis results or fever development. 1
Treatment Options at 10 Weeks Gestation
Surgical Evacuation (Preferred Method)
Suction dilation and curettage (D&C) is the safest option at this gestational age with prolonged retention, offering:
- Lower hemorrhage risk (9.1% vs 28.3% with medical management) 1
- Lower infection risk (1.3% vs 23.9% with medical management) 1
- Lower retained tissue requiring repeat procedure (1.3% vs 17.4% with medical management) 1
- Immediate resolution 2
Perform under ultrasound guidance to reduce uterine perforation risk. 2 Administer uterotonic agents during and after the procedure to minimize bleeding. 2
Medical Management (Alternative if Patient Prefers)
If the patient is hemodynamically stable without signs of infection and strongly prefers medical management:
- Vaginal misoprostol 800 mcg is more effective than oral administration 5, 6
- Success rate approximately 80% for missed abortion 7
- Vaginal route achieves higher success rates, shorter induction-to-expulsion intervals, and greater patient satisfaction compared to oral administration 6
- Alternative: 600 mcg sublingual misoprostol 5
However, given the 8-week retention period, surgical evacuation remains strongly preferred due to infection and coagulopathy risks. 1
Essential Pre-Procedure Workup
- Complete blood count to assess anemia and thrombocytopenia 2
- Blood type and Rh status: Administer 50 μg Rho(D) immunoglobulin if Rh-negative 1, 2
- Coagulation studies given prolonged retention 1
- Assess for signs of disseminated intravascular coagulation 1
Post-Procedure Follow-Up
- Serial hCG monitoring until return to non-pregnant state 2
- Ultrasound evaluation to confirm complete evacuation 2
- Histopathologic examination of tissue to confirm intrauterine pregnancy and rule out gestational trophoblastic disease 2, 4
Common Pitfalls to Avoid
- Never pursue expectant management with confirmed fetal demise and prolonged retention 1
- Do not delay evacuation waiting for fever or amniocentesis results if infection is suspected 3, 1
- Do not misdiagnose as incomplete abortion—careful ultrasound evaluation is essential to differentiate from ectopic pregnancy 1