What type of abortion is characterized by fetal death with no tissue expulsion for an extended period, such as 8 weeks, at 10 weeks of gestation?

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Missed Abortion (Aborto Retenido)

This clinical scenario describes a missed abortion (also termed "embryonic/fetal demise" or "aborto retenido"), defined as embryonic or fetal death without spontaneous expulsion of conception products. 1, 2

Diagnostic Classification

The Society of Radiologists in Ultrasound 2025 consensus guidelines establish that this presentation falls under "Diagnostic of Early Pregnancy Loss (EPL)" with the specific subcategory of embryonic/fetal demise when there is confirmed absence of cardiac activity with retained products of conception. 3 The key diagnostic features include:

  • Crown-rump length ≥7 mm without cardiac activity, OR
  • Mean sac diameter ≥25 mm without an embryo (anembryonic pregnancy), OR
  • Absence of embryo ≥14 days after visualization of gestational sac 3, 2

The term "missed abortion" remains clinically acceptable, though modern terminology favors "embryonic/fetal demise" (with "fetal demise" specifically used at ≥11 weeks gestation). 3, 1 Avoid obsolete terms like "blighted ovum" or "nonviable pregnancy." 3, 4

Critical Management Considerations at 10 Weeks with 8-Week Retention

Active evacuation is mandatory—expectant management is absolutely contraindicated in this scenario. 1 The prolonged retention (8 weeks since fetal death) creates substantial maternal risks:

Immediate Risks Requiring Urgent Intervention

  • Intrauterine infection risk increases significantly with time, particularly beyond 18 hours from diagnosis 1, 4
  • Coagulopathy risk from retained products 1
  • Maternal sepsis from prolonged tissue retention 1

Signs of Infection (Do NOT Wait for Fever)

Clinical symptoms of infection may be less overt at earlier gestational ages—do not delay treatment waiting for fever. 3, 1 Look for:

  • Maternal tachycardia
  • Purulent cervical discharge
  • Fetal tachycardia (if applicable)
  • Uterine tenderness 3, 1

If infection is suspected, initiate broad-spectrum antibiotics immediately and proceed with urgent evacuation. 1 Do not delay definitive treatment waiting for amniocentesis results or fever development. 1

Treatment Options at 10 Weeks Gestation

Surgical Evacuation (Preferred Method)

Suction dilation and curettage (D&C) is the safest option at this gestational age with prolonged retention, offering:

  • Lower hemorrhage risk (9.1% vs 28.3% with medical management) 1
  • Lower infection risk (1.3% vs 23.9% with medical management) 1
  • Lower retained tissue requiring repeat procedure (1.3% vs 17.4% with medical management) 1
  • Immediate resolution 2

Perform under ultrasound guidance to reduce uterine perforation risk. 2 Administer uterotonic agents during and after the procedure to minimize bleeding. 2

Medical Management (Alternative if Patient Prefers)

If the patient is hemodynamically stable without signs of infection and strongly prefers medical management:

  • Vaginal misoprostol 800 mcg is more effective than oral administration 5, 6
  • Success rate approximately 80% for missed abortion 7
  • Vaginal route achieves higher success rates, shorter induction-to-expulsion intervals, and greater patient satisfaction compared to oral administration 6
  • Alternative: 600 mcg sublingual misoprostol 5

However, given the 8-week retention period, surgical evacuation remains strongly preferred due to infection and coagulopathy risks. 1

Essential Pre-Procedure Workup

  • Complete blood count to assess anemia and thrombocytopenia 2
  • Blood type and Rh status: Administer 50 μg Rho(D) immunoglobulin if Rh-negative 1, 2
  • Coagulation studies given prolonged retention 1
  • Assess for signs of disseminated intravascular coagulation 1

Post-Procedure Follow-Up

  • Serial hCG monitoring until return to non-pregnant state 2
  • Ultrasound evaluation to confirm complete evacuation 2
  • Histopathologic examination of tissue to confirm intrauterine pregnancy and rule out gestational trophoblastic disease 2, 4

Common Pitfalls to Avoid

  • Never pursue expectant management with confirmed fetal demise and prolonged retention 1
  • Do not delay evacuation waiting for fever or amniocentesis results if infection is suspected 3, 1
  • Do not misdiagnose as incomplete abortion—careful ultrasound evaluation is essential to differentiate from ectopic pregnancy 1

References

Guideline

Aborto: Etiología, Clasificación, Características Clínicas, Diagnóstico y Tratamiento

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Miscarriage Diagnosis and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Anembryonic Pregnancy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Misoprostol to treat missed abortion in the first trimester.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2007

Research

Management of spontaneous abortion.

American family physician, 2005

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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