Treatment of Vertigo
For benign paroxysmal positional vertigo (BPPV)—the most common cause of vertigo—perform the Epley maneuver immediately, which achieves 90-98% success rates and is far superior to medications. 1, 2
Diagnosis First: Identify the Type of Vertigo
The treatment approach depends entirely on the underlying cause, which can be determined through specific bedside testing:
For BPPV (Most Common)
- Diagnose posterior canal BPPV using the Dix-Hallpike maneuver: bring the patient from upright to supine with head turned 45° to one side and neck extended 20°, looking for torsional upbeating nystagmus 3, 2
- Diagnose lateral canal BPPV using the supine roll test 1, 2
- BPPV presents as brief episodes (seconds to minutes) of spinning triggered by position changes like rolling over in bed, looking up, or bending over 3
For Ménière's Disease
- Characterized by episodic vertigo lasting 20 minutes to hours, accompanied by fluctuating hearing loss, tinnitus, and aural fullness 3
- Diagnosis is clinical based on this symptom complex 3
For Vestibular Neuronitis
- Presents as acute, continuous vertigo lasting hours to days with spontaneous nystagmus 4, 5
- No hearing loss (distinguishes from labyrinthitis) 4
Treatment Algorithm by Diagnosis
BPPV Treatment (First-Line)
Perform canalith repositioning maneuvers immediately—do not prescribe medications as primary treatment:
Posterior Canal BPPV (Most Common)
- Epley maneuver is the definitive treatment with 80-93% success after 1-3 treatments 1, 6, 2
- The sequence: patient seated with head turned 45° toward affected ear → rapidly move to supine with head hanging 20° below horizontal → turn head 90° to unaffected side → turn head and body another 90° (face down) → return to sitting 2
- Do not prescribe post-maneuver activity restrictions—they are unnecessary 2
Lateral Canal BPPV
Critical Pitfall to Avoid
- Do not use vestibular suppressants (meclizine) as primary BPPV treatment—they have only 30.8% efficacy compared to 78.6-93.3% for repositioning maneuvers 6
- Meclizine may only be considered for severe nausea/vomiting during the maneuver itself, used for maximum 3-5 days 6
Follow-Up
- Reassess within 1 month to document resolution or persistence 3, 1, 2
- If symptoms persist, re-evaluate for canal conversion (occurs in ~6% of cases), involvement of other canals, or alternative diagnoses 1, 2
Ménière's Disease Treatment
Start with dietary sodium restriction (1500-2300 mg daily) combined with diuretics as first-line preventive therapy: 6
Acute Attack Management
- Meclizine 25-100 mg daily in divided doses for short-term symptomatic relief during acute vertigo attacks 6, 7
- Limit alcohol and caffeine intake 6
Maintenance Therapy
- Diuretics and/or betahistine may be offered to reduce attack frequency 3, 6
- Betahistine increases inner ear vasodilation 6
Escalation for Treatment Failures
- Intratympanic steroids for active disease not responsive to noninvasive treatment 3
- Intratympanic gentamicin for definitive vertigo control in refractory cases, though this carries risk of hearing loss 3
- Surgical options (labyrinthectomy, vestibular nerve section) reserved for patients without useful hearing 3
Important Contraindication
- Do not prescribe positive pressure therapy (Meniett device)—randomized trials show it is ineffective 3
Vestibular Neuronitis/Labyrinthitis Treatment
- Short-term vestibular suppressants (meclizine 25-100 mg daily) for initial stabilization during acute phase 6, 4
- Corticosteroids for acute vestibular neuritis 8
- Transition to vestibular rehabilitation after acute symptoms stabilize 6, 4
Vestibular Rehabilitation Therapy (VRT)
Use VRT for persistent dizziness, chronic imbalance, or incomplete recovery from any vestibular cause—not for acute vertigo attacks: 3, 6
When to Prescribe VRT
- Persistent symptoms after BPPV treatment 1, 6
- Chronic imbalance in Ménière's disease (but not during acute attacks) 3
- Incomplete compensation after vestibular neuronitis 6, 4
VRT Components
- Cawthorne-Cooksey exercises: progressive eye, head, and body movements performed until symptoms fatigue, forcing central nervous system compensation through habituation 1
- Brandt-Daroff exercises for BPPV: rapid lateral head/trunk tilts (though significantly less effective than Epley maneuver: 25% vs 80.5% resolution) 2
- Home-based therapy is equally effective as clinician-supervised therapy after initial instruction 1
Safety Profile
- VRT is safe with no serious adverse events reported in clinical trials 1
- May decrease recurrence rates, particularly beneficial for elderly patients 1
Medication Guidelines and Critical Warnings
Meclizine (Vestibular Suppressant)
Prescribe meclizine only for short-term symptomatic relief in non-BPPV conditions or severe nausea—never as primary BPPV treatment:
FDA-Approved Dosing
- 25 mg to 100 mg daily in divided doses for vertigo associated with vestibular system diseases 7
- Maximum duration: 3-5 days 6
Contraindications
- Hypersensitivity to meclizine 7
- Use with caution in asthma, glaucoma, or prostate enlargement due to anticholinergic effects 6, 7
Adverse Effects (Particularly in Elderly)
- Drowsiness and cognitive deficits 6
- Anticholinergic effects (dry mouth, blurred vision) 7
- Increased fall risk—critical concern in elderly patients with vertigo 6
- Impaired driving ability 6, 7
Drug Interactions
- Avoid coadministration with other CNS depressants including alcohol—results in increased CNS depression 7
- CYP2D6 inhibitors may increase meclizine levels 7
Common Clinical Pitfalls
- Prescribing meclizine instead of performing repositioning maneuvers for BPPV—this is the most common error 6, 2
- Failing to reassess patients within 1 month after initial treatment 3, 2
- Missing canal conversions or multiple canal involvement in persistent BPPV 1, 2
- Prescribing vestibular suppressants long-term—they delay central compensation 6
- Using vestibular rehabilitation during acute Ménière's attacks—it is contraindicated 3