Differential Diagnosis for a 24-Year-Old Male Weightlifter with Moderate Intermittent Right Shoulder Pain
The most likely diagnoses in this young weightlifter are rotator cuff tendinopathy (without full-thickness tear), subacromial impingement syndrome, or AC joint pathology—all related to repetitive overhead or heavy lifting mechanics. 1, 2
Primary Differential Diagnoses
Rotator Cuff Tendinopathy/Impingement
- Most common cause of shoulder pain in active individuals, accounting for over two-thirds of shoulder pain cases 3, 2
- Presents with pain during overhead activities, lifting, or reaching behind the back 2
- Intermittent nature suggests inflammation without complete tear, typical in younger athletes 1, 4
- Pain often worsens with specific movements (abduction, internal/external rotation) rather than constant 2
Subacromial Bursitis
- Frequently coexists with rotator cuff pathology in weightlifters 5
- Causes pain with overhead pressing movements and lateral arm raises 3
- Inflammation from repetitive microtrauma during bench press, overhead press, or pull-ups 2
Acromioclavicular (AC) Joint Pathology
- Common in weightlifters from bench pressing and overhead movements 4
- Pain localizes to top of shoulder, worsens with cross-body adduction 2
- May have point tenderness directly over AC joint 4
Biceps Tendinopathy
- Anterior shoulder pain that may radiate down biceps 3
- Aggravated by curling movements or overhead activities 2
- Less common as isolated pathology in this age group 4
Less Likely but Important Considerations
Labral Tear (SLAP Lesion)
- Can occur from repetitive overhead lifting or acute trauma 4
- Typically causes clicking, catching, or deep shoulder pain 2
- More common with history of specific injury event 4
Glenohumeral Instability
- Rare without history of dislocation or subluxation 4
- Would present with sensation of shoulder "giving way" 2
- Unlikely with only intermittent pain during lifting 4
Adhesive Capsulitis (Frozen Shoulder)
- Extremely unlikely in a 24-year-old 5
- Accounts for only 6% of shoulder pain and predominantly affects older adults 5
- Would present with progressive stiffness and global range of motion loss 3
Critical Red Flags to Rule Out
Referred Pain from Cervical Spine
- Neck pathology can mimic shoulder pain 3
- Look for radiation into arm, numbness, or neck movement reproducing symptoms 2
Glenohumeral Osteoarthritis
- Essentially impossible at age 24 without prior trauma 5
- Accounts for only 2-5% of shoulder pain in general population 5
Avascular Necrosis
- Requires risk factors: corticosteroid use, alcohol abuse, trauma 5
- Would present with constant, progressive pain 3
Diagnostic Approach
Physical examination findings are more valuable than imaging in this population 1, 2:
- Painful arc test (60-120 degrees abduction): suggests subacromial impingement 2
- Neer and Hawkins-Kennedy tests: positive in rotator cuff impingement 3
- Cross-body adduction test: isolates AC joint pathology 2
- Empty can test (Jobe's test): assesses supraspinatus tendon 3
- Speed's and Yergason's tests: evaluate biceps tendon 2
Imaging is not immediately necessary unless trauma occurred or symptoms persist beyond 6-8 weeks of conservative treatment 1, 4. Plain radiographs would be first-line if imaging needed, followed by ultrasound or MRI only if surgical intervention considered 3, 4.
Most Probable Diagnosis
In a 24-year-old weightlifter with intermittent pain, rotator cuff tendinopathy with subacromial impingement is the overwhelming favorite, representing the intersection of age, activity pattern, and symptom description 1, 3, 2. The intermittent nature strongly suggests inflammation without structural tear, which is typical for this demographic 4, 5.