Treatment of Callus
Professional scalpel debridement by a trained healthcare provider is the gold standard treatment for callus, which should be combined with addressing underlying mechanical causes through appropriate footwear and orthotic devices. 1, 2
Primary Treatment: Professional Debridement
- Sharp scalpel debridement removes all callus tissue and is the cornerstone of management, as it reduces plantar pressure (a key risk factor for ulceration) and prevents complications 3, 2, 4
- Debridement must be performed by an appropriately trained healthcare professional to avoid potential harm, particularly in high-risk patients 3
- The procedure showed immediate and significant improvements in skin hydration, elasticity, texture, and associated foot pain in controlled trials 4
- Repeat debridement every 1-3 months for high-risk patients (diabetics, peripheral arterial disease) and every 3-6 months for moderate-risk patients 1, 2
Addressing Mechanical Causes (Essential for Prevention)
After debridement, you must address why the callus formed:
- Prescribe custom-made footwear, custom-made insoles, or orthotic devices for patients with foot deformities or recurrent calluses 3, 1, 2
- Toe silicone devices and semi-rigid orthotic devices redistribute pressure and reduce callus formation on toes 3, 1
- The shoe should be 1-2 cm longer than the foot, with internal width equal to the foot width at the metatarsal phalangeal joints 3
- Evaluate footwear fit with the patient standing, preferably at the end of the day 3
Home Care and Prevention
- Apply emollients daily to maintain skin hydration and elasticity, but never between the toes (risk of maceration) 3, 2, 5
- Daily foot inspection to identify early callus development, especially for diabetic patients 1, 2, 5
- Daily lukewarm baths (30 minutes or more) with gentle scale removal using sponges, microfiber cloths, or pumice stone 3
- Never walk barefoot, in socks only, or in thin-soled slippers, whether indoors or outdoors 3, 5
Topical Keratolytic Agents (Adjunctive)
While professional debridement is primary, keratolytics may be used as adjuncts:
- Salicylic acid 6% can be applied to affected areas at night after washing, with the medication washed off in the morning 6
- Urea (≥10%) may be used, but not recommended before age 1 year except on limited areas like palms and soles 3
- A combination product containing 1% cantharidin, 30% salicylic acid, and 5% podophyllin showed 79.2% success in one session when applied after tangential excision 7
- Potassium hydroxide (<10%) products showed safety and effectiveness when applied for 3-5 minutes before filing 8
Special Considerations for High-Risk Patients
In diabetic patients, calluses are pre-ulcerative lesions requiring immediate treatment to prevent ulceration 3, 1, 2:
- More conservative debridement approach due to higher complication risk 2, 5
- Integrated foot care including professional removal, appropriate footwear, and structured education 1, 2
- If one or more pedal pulses are absent, perform extensive vascular evaluation before aggressive debridement 3
- Therapeutic footwear is mandatory for high-risk patients 5
Surgical Options for Refractory Cases
When non-surgical treatments fail:
- Consider digital flexor tendon tenotomy for non-rigid hammertoes with callus on the apex or distal toe 3, 1, 2
- This procedure is easily performed in an outpatient setting with no need for immobilization 3
- Surgery should only be considered after full evaluation of non-surgical options by an appropriately trained healthcare professional 3, 1
Critical Pitfalls to Avoid
- Never allow patients to self-treat with chemical corn removers or plasters—this increases infection and ulceration risk 3, 2, 5
- Do not cut corns or calluses at home; professional care is essential 2, 5
- Avoid applying moisturizers between toes, as this increases maceration risk 2, 5
- Do not use iodine-based antiseptics (risk of thyroid dysfunction) 3