Is anterior cervical discectomy and fusion (ACDF) medically indicated for a patient with neck pain and right upper extremity radiculopathy due to a disc bulge with uncovertebral arthropathy at the C5-6 level, who has failed nonoperative treatment, including epidural steroid injections (ESI)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: November 20, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Medical Necessity Determination for C5-6 ACDF

Yes, anterior cervical discectomy and fusion (ACDF) at C5-6 is medically indicated for this patient with cervical radiculopathy who has failed conservative management including epidural steroid injection. 1

Criteria Met for Surgical Intervention

This patient satisfies all three required criteria for ACDF:

I. Significant Symptoms Due to Nerve Root Compression

  • Right upper extremity radiculopathy with C6 dermatomal distribution (numbness extending to lateral arm and thumb) correlates precisely with C5-6 pathology 1
  • Motor weakness manifesting as decreased hand grip strength represents functional impairment 1
  • Neck pain radiating to shoulder and shoulder blade with sensory dysfunction constitutes significant symptoms impacting quality of life 1

II. Imaging Correlation with Clinical Presentation

  • MRI demonstrates disc bulge with uncovertebral arthropathy at C5-6 causing moderate central canal stenosis and severe right foraminal stenosis 1
  • The severe right foraminal stenosis directly correlates with right-sided C6 radicular symptoms 1
  • This anatomic-clinical correlation is essential, as MRI findings must always match symptom distribution 1

III. Failed Conservative Management

  • One epidural steroid injection without relief documents failed non-operative treatment 1
  • While guidelines typically recommend 6+ weeks of conservative therapy, the patient has documented trial of epidural corticosteroids as specified in the criteria 1
  • 75-90% of cervical radiculopathy patients improve with conservative management, but this patient falls into the 10-25% requiring surgery 1

Surgical Efficacy Evidence

ACDF provides 80-90% success rates for arm pain relief and achieves more rapid symptom resolution (within 3-4 months) compared to continued conservative treatment 1

  • 90.9% functional improvement has been reported following surgical intervention for cervical radiculopathy with significant functional deficits 1
  • ACDF specifically addresses the pathology at C5-6 by removing disc material and decompressing the neural foramen 2
  • The procedure is particularly effective for foraminal stenosis caused by uncovertebral joint arthropathy, which is this patient's primary pathology 1

Instrumentation and Fusion Device Justification

Anterior cervical plating (instrumentation) is medically necessary for this single-level fusion to reduce pseudarthrosis risk and maintain cervical lordosis 1

  • The addition of anterior cervical plate reduces graft problems and maintains proper alignment, which is critical for sustained foraminal decompression 1
  • Interbody cage placement provides immediate structural support and maintains disc height, essential for adequate neural foraminal dimensions 1
  • For single-level ACDF, instrumentation demonstrates Class II-III evidence supporting its use 1

Critical Considerations

Posterior Disc Height Restoration

  • Maintaining posterior disc height is more critical than excessive lordosis restoration for patients with foraminal stenosis 3
  • Cage placement in a relatively posterior position helps preserve posterior disc space height and foraminal dimensions 3

Alternative Approaches Not Indicated

  • Posterior laminoforaminotomy is reserved for soft lateral disc herniations or when anterior approach is contraindicated 1
  • This patient has uncovertebral arthropathy (hard disc pathology) with central canal involvement, making anterior approach superior 1, 4

Common Pitfalls to Avoid

  • Do not delay surgery in patients with progressive motor weakness, as this represents a relative urgency for intervention 1
  • Ensure cage placement maintains posterior disc height rather than focusing solely on lordotic angle restoration 3
  • Verify that symptoms correlate with the surgical level before proceeding, as anatomic mismatch leads to poor outcomes 1
  • Document specific conservative treatments attempted with dates and response, though this patient has documented ESI failure 1

References

Guideline

Cervical Radiculopathy Diagnosis and Treatment

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

UPPER CERVICAL RADICULOPATHY: THE HIDDEN PATHOLOGY OF THE SPINE.

Spine surgery and related research, 2018

Related Questions

Is anterior cervical discectomy and fusion (ACDF) with removal of instrumentation at C6-7 and insertion of spine fixation devices at C5-6 medically indicated for a patient with cervical radiculopathy, neuroforaminal stenosis, and symptoms of numbness, tingling, and weakness in the right arm?
Is a C4-5 anterior cervical discectomy and fusion (ACDF) medically necessary for a patient with radiculopathy in the cervical region, moderate to severe central canal and foraminal stenosis, and failed conservative therapy?
Is a C4-5 anterior cervical discectomy fusion (ACDF) with spine bone allograft morsel add-on and insertion of a spine fixation device medically necessary for a patient with radiculopathy, cervical region, who has failed conservative treatment and has significant symptoms and diagnostic findings?
Is cervical anterior cervical discectomy and fusion (ACDF) medically necessary for a patient with cervical spondylosis, radiculopathy, and spinal stenosis, who has failed conservative management with physical therapy, oral corticosteroids (e.g. Medrol Dosepak (methylprednisolone)), and nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g. Meloxicam, Naproxen)?
What is the step-by-step procedure for Anterior Cervical Discectomy and Fusion (ACDF) of the C5-C6 interspace for treatment of a Protruded Intervertebral Disc (PIVD)?
What is the management approach for a patient presenting with seizure-like activity, hypodensities in the right parietal lobe, and dilated perivascular spaces?
What medications should be held before a uteroscopy, including anticoagulants (e.g. warfarin), antiplatelet agents (e.g. aspirin, clopidogrel), and non-steroidal anti-inflammatory drugs (NSAIDs) (e.g. ibuprofen)?
Is lithium effective for treating Alzheimer's disease?
What are the potential interactions between Strattera (atomoxetine), Lamictal (lamotrigine), and Clonidine when used together?
What treatment options are available for individuals experiencing depression, anxiety, and low energy?
What are the indications for a permanent urinary catheter for a patient?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.